DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	102/264 - (38%)
Similarity:	145/264 - (54%)	Gaps:	36/264 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 CGERN---DESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFM------ 174
            ||.|.   ...::.||......|:||.|.|...|...||.|||::.:::|||||   |:
  Rat   175 CGRRTITPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHC---FVRSANPK 236

  Fly   175 -WFMIKVTFGEHDRCNDKERPETRFVLRA--FSQKFSFSNFDNDIALLRLNDRVPITSFIRPICL 236
             |   ||:||..     ..:|:.:..:::  ..:.:|:...:||||::||:..|...:.||..||
  Rat   237 DW---KVSFGFL-----LSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACL 293

  Fly   237 PRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSG 301
            |  |..|.....:..:.|||||||.||....:||:..|.::||..|.:...| ..:||..|:|:|
  Rat   294 P--EATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAY-GGVITPGMLCAG 355

  Fly   302 YPGVGGR-DSCQGDSGGPLVRLRPDDKR--FEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVEN 363
            :  :.|| |:||||||||||   .:|.:  :...||||||:.||.||.||||||||.|.|||  :
  Rat   356 F--LEGRVDACQGDSGGPLV---SEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI--S 413

  Fly   364 SRDG 367
            |:.|
  Rat   414 SKTG 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	95/244 (39%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	97/246 (39%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	95/244 (39%)
		Tryp_SPc	187..415	CDD:238113	97/248 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960