DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and proca

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	291	Identity:	99/291 - (34%)
Similarity:	153/291 - (52%)	Gaps:	46/291 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 TCSC-----------RCGERNDES---------------------RIVGGTTTGVSEYPWMAR-L 145
            ||||           :|..:||.|                     .::||......|.||.|. |
Zfish   149 TCSCIKGYQLQDNSRKCTPKNDASCGQIRIPKSAYANKPKPVLQPWVMGGNVGKRGESPWQALIL 213

  Fly   146 SYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQ-KFSF 209
            ::..||:|||.||::.:|||||||::....|.:::  |::.|...:....|..|.:..|. :::.
Zfish   214 NHLGRFHCGGVLIDENWVLTAAHCLETSSKFSVRL--GDYQRFKFEGSEVTLPVKQHISHPQYNP 276

  Fly   210 SNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQDLF--VGTKAIATGWGTLKEDGKP-SCLLQE 271
            ...|||||||||:..|..:::|.|.|||.:|..:.:.  .||..|.||||...:.... :..|..
Zfish   277 ITVDNDIALLRLDGPVKFSTYILPACLPSLELAKRMLHRNGTVTIITGWGKNNQSATSYNSTLHY 341

  Fly   272 VEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVS 336
            ||:|::||.||   :.:....::.||:|:|..| ..:|:|:||||||::.|..|  .:..:|:||
Zfish   342 VELPIVDNKEC---SRHMMNNLSDNMLCAGVLG-QVKDACEGDSGGPMMTLFHD--TWFLVGLVS 400

  Fly   337 WGNGCARPNYPGVYTRVTKYLDWIVENSRDG 367
            ||.||.:.:..|:||:|..||||| ::.|.|
Zfish   401 WGEGCGQRDKLGIYTKVASYLDWI-DSVRQG 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	87/237 (37%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	89/239 (37%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342	4/15 (27%)
		Tryp_SPc	195..427	CDD:238113	89/240 (37%)
		Tryp_SPc	197..424	CDD:214473	87/234 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910