DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and ndl

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	91/250 - (36%)
Similarity:	137/250 - (54%)	Gaps:	27/250 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 ESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCN 189
            :.|||||:.|...::|::..:....:|:||||:.:||::::|||||..:..:..:|..|...|.:
  Fly  1142 DGRIVGGSYTSALQWPFVVAIYRNGKFHCGGTIYSDRWIISAAHCVINYGKYFYEVRAGLLRRSS 1206

  Fly   190 ----DKERPETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSFIRPICLP---RVEQRQDLFV 247
                .:.:|.:..|:.   |.:...:..||::||||.:.:....:::|||||   |.....|...
  Fly  1207 YSPATQIQPVSHVVVH---QAYERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTVGDDWIW 1268

  Fly   248 G----TKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGR 308
            |    |.....|||.::|.|..|..:::|.||:  ..:|....:...:.|     |:|.|. |||
  Fly  1269 GPVEHTLCTVVGWGAIREKGPSSDPMRQVIVPI--RKKCTDPEDQASEDI-----CAGDPD-GGR 1325

  Fly   309 DSCQGDSGGPLV---RLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWI 360
            |:|||||||||.   ...||:  |...|:||.|||||||...|||||||.||||:
  Fly  1326 DACQGDSGGPLFCRSVSNPDE--FYLAGVVSHGNGCARPQEFGVYTRVTLYLDWL 1378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	90/246 (37%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	90/246 (37%)
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	89/245 (36%)
		Tryp_SPc	1145..1379	CDD:238113	90/246 (37%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010