DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001004020.1	Gene:	Tmprss11b / 365265	RGDID:	1303278	Length:	420	Species:	Rattus norvegicus

Alignment Length:	339	Identity:	107/339 - (31%)
Similarity:	156/339 - (46%)	Gaps:	89/339 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 TSSLSSIPGKYQALGAAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFNRNNSPAAQNQT 111
            :.||::.||             .||:.::  :..||.|.:               ||
  Rat   148 SGSLTTDPG-------------SLKLTEI--TKVDAEKII---------------NN-------- 174

  Fly   112 SPTCSCRCGERNDES----RIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKG 172
                  |||.|...|    ||.||:|....|:||.|.|....:.:||.:||.:|::||||||
  Rat   175 ------RCGRRPRMSATYDRITGGSTAQKGEWPWQASLRVNGKHHCGASLIGERFLLTAAHC--- 230

  Fly   173 FMWFM-------IKVTFGEHDRCNDKERPETRFVLRAFSQ----------KFSFSNFDNDIALLR 220
               |:       :.|:||            || |..|:.|          .:......:|:|:::
  Rat   231 ---FLRTNNPKNLTVSFG------------TR-VTPAYMQHYVEEVIIHEDYVKGQHHDDVAIIK 279

  Fly   221 LNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQ 285
            |.::|...:.:..:|||  |..|....|...:.||||:|..:||...|||:..:.::|.:.|.::
  Rat   280 LTEKVSFRNDVHRVCLP--EATQVFPPGEGVVVTGWGSLSYNGKSPLLLQKASIKIIDTNACNSE 342

  Fly   286 TNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVY 350
            ..|..: |...|:|:||. .|..|:||||||||||.....|..: .:||||||:.|.|.|.||||
  Rat   343 EAYGGR-IMDTMLCAGYM-EGYVDACQGDSGGPLVHPNSRDIWY-LVGIVSWGHECGRVNKPGVY 404

  Fly   351 TRVTKYLDWIVENS 364
            .|||.|.|||...:
  Rat   405 MRVTSYRDWIASKT 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	89/249 (36%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	90/251 (36%)
Tmprss11b	NP_001004020.1	SEA	50..144	CDD:279699
		Tryp_SPc	188..414	CDD:214473	89/249 (36%)
		Tryp_SPc	189..417	CDD:238113	90/251 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920