DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and prss60.3

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	248	Identity:	101/248 - (40%)
Similarity:	138/248 - (55%)	Gaps:	14/248 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 CGERNDESRIVGGTTTGVSEYPWMARL--SYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVT 181
            ||:....:|||||.......:||...|  ..:...:|||:||:..:|||||||:.|.....:.|.
Zfish    27 CGQAPLNTRIVGGVNASPGSWPWQVSLHSPKYGGHFCGGSLISSEWVLTAAHCLSGVSETTLVVY 91

  Fly   182 FGEHDRCNDKERPETRFVLRAF-SQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQDL 245
            .|...:........:|.|.::| ...::.:..|||||||||:..|..|::|||:||  ..|....
Zfish    92 LGRRTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCL--AAQNSVY 154

  Fly   246 FVGTKAIATGWGTLKED-GKPS-CLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGR 308
            ..||.:..||||.::.. ..|: .:|||..:||:.||.|.|...  ...:|.||:|:|.. .||:
Zfish   155 SAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRCNALLG--SGTVTNNMICAGLT-QGGK 216

  Fly   309 DSCQGDSGGPLV-RLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWI 360
            |:||||||||:| ||   ...:.|.||.|||.|||.||.|||||||::|..||
Zfish   217 DTCQGDSGGPMVTRL---CTVWVQAGITSWGYGCADPNSPGVYTRVSQYQSWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	97/238 (41%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	98/239 (41%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	98/239 (41%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.000