DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	95/268 - (35%)
Similarity:	136/268 - (50%)	Gaps:	36/268 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 CSCRCGERNDES-RIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCV-------- 170
            ||. ||.|...| |||||..:.::::||...|.:.....|||::|...:::||||||
  Rat   204 CSA-CGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHPKS 267

  Fly   171 ----KGFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSFI 231
                .|.:..|            |...|........:..|:......|||||::|::.:.....|
  Rat   268 WTVQVGLVSLM------------DSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETI 320

  Fly   232 RPICLPRVEQR-QDLFVGTKAIATGWGTLKED-GKPSCLLQEVEVPVLDNDECVAQTNYTQKMIT 294
            :|||||..|:. .|   |.....:|||..::. |..|.:|....||::.|..|..:..| ..:|:
  Rat   321 QPICLPNSEENFPD---GKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVY-GGIIS 381

  Fly   295 KNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDW 359
            .:|:|:||. .||.||||||||||||  ..:.:.::.:|..|:|.|||..|.||||||:|.:|||
  Rat   382 PSMLCAGYL-KGGVDSCQGDSGGPLV--CQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDW 443

  Fly   360 IVEN-SRD 366
            |.|. .||
  Rat   444 IHEQLERD 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	84/246 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	85/248 (34%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	4/7 (57%)
		Tryp_SPc	216..444	CDD:214473	84/246 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.960