DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001008554.1	Gene:	Tmprss11g / 289546	RGDID:	1306446	Length:	417	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	89/262 - (33%)
Similarity:	137/262 - (52%)	Gaps:	20/262 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 AAQNQTSPTCSCRCG-ERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHC 169
            |||.:.....:|..| |....:||..|...|.:.:||.:.|.......||.:||..::::|:|||
  Rat   163 AAQAEHILNSNCGLGMEYPRIARIADGKPAGSNSWPWQSSLQVEGIHLCGASLIGSQWLVTSAHC 227

  Fly   170 VKGF----MWFMIKVTFGEHDRCNDKERPETRFVLRA--FSQKFSFSNFDNDIALLRLNDRVPIT 228
            ...:    :|   .|:||     .....|.|...:.:  ..:.::....|:|||:::|:..|..:
  Rat   228 FDNYKNPKLW---TVSFG-----RTLGNPLTTRKVESIIIHENYAAHKHDDDIAVVKLSSPVLFS 284

  Fly   229 SFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMI 293
            ..:|.:|||  |....:...:|...||||.||.:|.....|||||:.::.||.| .|.|.....|
  Rat   285 ENLRTVCLP--EATFQVLPKSKVFVTGWGALKANGPFPNSLQEVEIEIISNDVC-NQVNVYGGAI 346

  Fly   294 TKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLD 358
            :..|:|:|:. .|..|:|:|||||||| :..:..::..:||||||..|.:.|.||:|||||.|.:
  Rat   347 SSGMICAGFL-TGKLDACEGDSGGPLV-ISDNRNKWYLLGIVSWGIDCGKENKPGIYTRVTHYRN 409

  Fly   359 WI 360
            ||
  Rat   410 WI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	81/238 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	82/239 (34%)
Tmprss11g	NP_001008554.1	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	81/238 (34%)
		Tryp_SPc	186..414	CDD:238113	82/239 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920