DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and f7i

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_775335.1	Gene:	f7i / 282671	ZFINID:	ZDB-GENE-021206-10	Length:	443	Species:	Danio rerio

Alignment Length:	291	Identity:	91/291 - (31%)
Similarity:	127/291 - (43%)	Gaps:	61/291 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 TCSCR-------------------CG-----ERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCG 154
            :|||.                   ||     :...:::.:||........||...:.|.....||
Zfish   148 SCSCAEGYALADDGTSCVSQVDYPCGKIPVQKNTSQNQFLGGIHCPRGHCPWQVLIDYNGESVCG 212

  Fly   155 GTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDR--CNDKERPETRFVLRAFSQKFSFSNF----- 212
            |.|:...:::||||||.......:|...||||.  .:..|.|      ...|..|...|:
Zfish   213 GALLEGPWLITAAHCVHQKDTRFLKAVTGEHDLDVLDGSEEP------YEVSAVFIHPNYDPETL 271

  Fly   213 DNDIALLRLNDRVPI--TSFIRPICLPRVE-QRQDLFVGTKAIATGWGT------LKED----GK 264
            |:|:|||||  |||:  :.:..|||||..: .|.:|:.......:||||      |:.:    |.
Zfish   272 DSDLALLRL--RVPVQRSLYAVPICLPTPQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKGP 334

  Fly   265 PSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRF 329
            .|..||.:.||:|...:| ...|     .|.||.|:||. .|...||:|..|.||| .|..:..|
Zfish   335 ASGTLQRLAVPLLPAAQC-GNAN-----TTANMFCAGYT-EGDHASCRGHDGSPLV-TRYGETSF 391

  Fly   330 EQIGIVSWGNGCARPNYPGVYTRVTKYLDWI 360
             ..|:||||.||..|.|..:||:|..:|.|:
Zfish   392 -LTGVVSWGRGCGPPGYYWIYTKVENFLIWM 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	85/252 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	86/253 (34%)
f7i	NP_775335.1	GLA	20..82	CDD:214503
		EGF_CA	<91..120	CDD:238011
		FXa_inhibition	129..164	CDD:291342	3/15 (20%)
		Tryp_SPc	188..420	CDD:214473	85/248 (34%)
		Tryp_SPc	188..420	CDD:238113	85/248 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000