DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss11e

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_766468.1	Gene:	Tmprss11e / 243084	MGIID:	3513175	Length:	423	Species:	Mus musculus

Alignment Length:	320	Identity:	108/320 - (33%)
Similarity:	154/320 - (48%)	Gaps:	55/320 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 KYQALGAAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCG 120
            || |.|..:...:.:||..:|.:.||            |:|.                  .| ||
Mouse   146 KY-ATGPPNVDPESVKIKKINKTESD------------NYFN------------------HC-CG 178

  Fly   121 ERNDES------RIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGF----MW 175
            .|.::|      ||||||.....|:||.:.|.:.....||.||||:.:::|||||.:..    .|
Mouse   179 TRRNKSTVQTSVRIVGGTPVEEEEWPWQSSLRWDGSHRCGATLINNTWLVTAAHCFRTHKDPSRW 243

  Fly   176 FMIKVTFGEHDRCNDKERPETRFVLRAF-SQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRV 239
               ..|||    ...:.|..|..:.|.. .:|:.:.:.|.||||..|:..||.|:.:..:|||
Mouse   244 ---SATFG----ATLQPRKLTTGIRRIIVHEKYKYPSHDYDIALAELSKPVPCTNAVHKVCLP-- 299

  Fly   240 EQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPG 304
            :...:...|.:...||:|.||.||.....|::|:|..:|...|....:| ...||..|:|:|:.
Mouse   300 DANHEFQPGQRMFVTGFGALKNDGFTQNNLRQVQVDYIDTQTCNQPQSY-NGAITPRMLCAGFL- 362

  Fly   305 VGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVENS 364
            .|.:|:||||||||||.....|..: ..|:||||:.|.:||.||||||||.:..||..|:
Mouse   363 KGEKDACQGDSGGPLVTADVRDIWY-LAGVVSWGDECGQPNKPGVYTRVTAFRHWIASNT 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	89/237 (38%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	90/239 (38%)
Tmprss11e	NP_766468.1	SEA	50..145	CDD:279699
		Tryp_SPc	191..417	CDD:214473	89/237 (38%)
		Tryp_SPc	192..420	CDD:238113	90/239 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3995
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960