DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss15

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_032967.1	Gene:	Tmprss15 / 19146	MGIID:	1197523	Length:	1069	Species:	Mus musculus

Alignment Length:	316	Identity:	103/316 - (32%)
Similarity:	157/316 - (49%)	Gaps:	40/316 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LKIGDVNAS---SSDANKPVFRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCR---CGER----ND 124
            |.:|..|:|   ||....|..|.|...|  |:.....|......:.....|.   |||:    ..
Mouse   764 LGLGSANSSMPISSTGGGPFVRVNQAPN--GSLILTPSLQCSQDSLILLQCNHKSCGEKKVTQKV 826

  Fly   125 ESRIVGGTTTGVSEYPWMARLSY----FNRFYCGGTLINDRYVLTAAHCV-----KGFMWFMIKV 180
            ..:||||:......:||:..|.:    .:|..||.:|::..::::|||||     ....|..:
Mouse   827 SPKIVGGSDAQAGAWPWVVALYHRDRSTDRLLCGASLVSSDWLVSAAHCVYRRNLDPTRWTAV-- 889

  Fly   181 TFGEHDRCNDKERPETRFVLRAFSQKFSFSNFD-----NDIALLRLNDRVPITSFIRPICLPRVE 240
             .|.|.:.|   ....:.|.|...|.....::|     ||||::.|..:|..|.:|:|||||  |
Mouse   890 -LGLHMQSN---LTSPQVVRRVVDQIVINPHYDRRRKVNDIAMMHLEFKVNYTDYIQPICLP--E 948

  Fly   241 QRQDLFVGTKAIATGWGTLK-EDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPG 304
            :.|....|......|||..| ..|....:|:|.:||::.|::|  |....:..||::|:|:||.
Mouse   949 ENQIFIPGRTCSIAGWGYDKINAGSTVDVLKEADVPLISNEKC--QQQLPEYNITESMICAGYE- 1010

  Fly   305 VGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWI 360
            .||.|||||||||||  :..::.|:..:|:.|:|..||.||:||||.||:::::||
Mouse  1011 EGGIDSCQGDSGGPL--MCQENNRWFLVGVTSFGVQCALPNHPGVYVRVSQFIEWI 1064

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	85/247 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	87/248 (35%)
Tmprss15	NP_032967.1	SEA	53..154	CDD:214554
		LDLa	228..261	CDD:197566
		CUB	270..376	CDD:294042
		MAM	392..549	CDD:279023
		MAM	392..547	CDD:99706
		CUB	569..676	CDD:278839
		LDLa	688..722	CDD:238060
		SR	723..816	CDD:214555	13/53 (25%)
		SRCR	728..819	CDD:278931	14/56 (25%)
		Tryp_SPc	829..1064	CDD:214473	85/247 (34%)
		Tryp_SPc	830..1066	CDD:238113	87/248 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11120
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910