DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and svh-1

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	89/283 - (31%)
Similarity:	140/283 - (49%)	Gaps:	54/283 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 NQTSPTCSCRCGERNDE-----------SRIVGGTTTGVSEYPWMARLSYFNR----FYCGGTLI 158
            :|...:.:.:||.|..|           :|:|||..|....:||.|.|.  |:    .:||.:::
Worm   683 SQNGMSSASQCGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALR--NKATKAHHCGASIL 745

  Fly   159 NDRYVLTAAHC------VKGFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSF-----SNF 212
            :..:::|||||      |..:     :|..|:.|. |..:..|..|.|    |:..|     ..|
Worm   746 DKTHLITAAHCFEEDERVSSY-----EVVVGDWDN-NQTDGNEQIFYL----QRIHFYPLYKDIF 800

  Fly   213 DNDIALLRL-NDRVPITSFIRPICLPRVEQRQDLFV---GTKAIATGWGTLKEDG-KPSCLLQEV 272
            .:|||:|.: ...:....:.:|||||..:     ||   |.:.:.:|||::   | :.:..||..
Worm   801 SHDIAILEIPYPGIEFNEYAQPICLPSKD-----FVYTPGRQCVVSGWGSM---GLRYAERLQAA 857

  Fly   273 EVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSW 337
            .:|:::..:||..:.....| :::..|:||. .||.||||||||||.. .|.:|..|...|::||
Worm   858 LIPIINRFDCVNSSQIYSSM-SRSAFCAGYL-EGGIDSCQGDSGGPFA-CRREDGAFVLAGVISW 919

  Fly   338 GNGCARPNYPGVYTRVTKYLDWI 360
            |:|||:...||:||.|..||.||
Worm   920 GDGCAQKKQPGIYTMVAPYLSWI 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	82/252 (33%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	83/253 (33%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	83/253 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910