DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	93/283 - (32%)
Similarity:	136/283 - (48%)	Gaps:	51/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 SPTCSCR---------CGERN--DESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLT 165
            |.:||.|         ||.|:  .:||||||:|....::||...|.......|||::|...:::|
  Rat   227 SDSCSSRMVVSLRCIECGVRSVRRQSRIVGGSTASPGDWPWQVSLHVQGIHVCGGSIITPEWIVT 291

  Fly   166 AAHCVK-------------GFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFD---- 213
            |||||:             |.:...:......|.                ..:..|..|:|
  Rat   292 AAHCVEEPLSSPRYWTAFAGILKQSLMFYGSRHQ----------------VEKVISHPNYDSKTK 340

  Fly   214 -NDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVL 277
             |||||::|...:.....::|:|||......||  ..:...:|||...|.||.|.:|....||::
  Rat   341 NNDIALMKLQTPLAFNDVVKPVCLPNPGMMLDL--AQECWISGWGATYEKGKTSDVLNAAMVPLI 403

  Fly   278 DNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCA 342
            :..:|.::..| ..:||..|:|:|:. .|..||||||||||||.|:  ::.:..||..|||:|||
  Rat   404 EPSKCNSKYIY-NNLITPAMICAGFL-QGSVDSCQGDSGGPLVTLK--NEIWWLIGDTSWGSGCA 464

  Fly   343 RPNYPGVYTRVTKYLDWIVENSR 365
            :...||||..||.:.|||.:..|
  Rat   465 KAYRPGVYGNVTVFTDWIYQQMR 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	82/250 (33%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	83/252 (33%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:292133	6/19 (32%)
		Tryp_SPc	253..482	CDD:214473	82/250 (33%)
		Tryp_SPc	254..485	CDD:238113	83/252 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960