DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	267	Identity:	95/267 - (35%)
Similarity:	136/267 - (50%)	Gaps:	35/267 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 CSCRCGERNDES-RIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCV-------- 170
            ||. ||.|...| |||||..:.::::||...|.:.....|||::|...:::||||||
Mouse   226 CSA-CGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYHPKS 289

  Fly   171 ----KGFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSFI 231
                .|.:..|            |...|........:..|:......|||||::|::.:.....|
Mouse   290 WTVQVGLVSLM------------DSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETI 342

  Fly   232 RPICLPRVEQR-QDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITK 295
            :|||||..|:. .|   |.....:|||..::.|..|.:|....||::.|..|..:..| ..:|:.
Mouse   343 QPICLPNSEENFPD---GKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVY-GGIISP 403

  Fly   296 NMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWI 360
            :|:|:||. .||.||||||||||||  ..:.:.::.:|..|:|.|||..|.||||||:|.:||||
Mouse   404 SMLCAGYL-KGGVDSCQGDSGGPLV--CQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWI 465

  Fly   361 VEN-SRD 366
            .|. .||
Mouse   466 HEQLERD 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	84/245 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	85/247 (34%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133	4/7 (57%)
		Tryp_SPc	238..465	CDD:214473	84/245 (34%)
		Tryp_SPc	239..468	CDD:238113	85/247 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11120
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910