DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and F9

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_032005.1	Gene:	F9 / 14071	MGIID:	88384	Length:	471	Species:	Mus musculus

Alignment Length:	307	Identity:	95/307 - (30%)
Similarity:	161/307 - (52%)	Gaps:	28/307 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 HQAKKLKIGDVNASSSD---ANKPVFRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCGERNDES 126
            :.:||:...:...|:.|   :.:.||.|:.|.:  ||...|.:.::::            .||.:
Mouse   185 YSSKKITRAETVFSNMDYENSTEAVFIQDDITD--GAILNNVTESSES------------LNDFT 235

  Fly   127 RIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCNDK 191
            |:|||......:.||...|:.....:|||.:||:::::|||||:|  ....|:|..||::....:
Mouse   236 RVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLK--PGDKIEVVAGEYNIDKKE 298

  Fly   192 ERPETRFVLRAF---SQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAIA 253
            :..:.|.|:|..   ....:.:.:.:|||||.|:..:.:.|::.|||:...|.............
Mouse   299 DTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANREYTNIFLKFGSGYV 363

  Fly   254 TGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGP 318
            :|||.:...|:.:.:||.:.||::|...|:..|.:|   |..||.|:|| ..||:|||:||||||
Mouse   364 SGWGKVFNKGRQASILQYLRVPLVDRATCLRSTTFT---IYNNMFCAGY-REGGKDSCEGDSGGP 424

  Fly   319 LVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVENSR 365
            .| ...:...| ..||:|||..||.....|:||:|::|::||.|.::
Mouse   425 HV-TEVEGTSF-LTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	79/235 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	80/237 (34%)
F9	NP_032005.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:291342
		Tryp_SPc	236..464	CDD:214473	79/235 (34%)
		Tryp_SPc	237..467	CDD:238113	80/237 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I3752
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11114
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910