DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and F10

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001229297.1	Gene:	F10 / 14058	MGIID:	103107	Length:	493	Species:	Mus musculus

Alignment Length:	265	Identity:	100/265 - (37%)
Similarity:	141/265 - (53%)	Gaps:	36/265 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 NQTSPTCSCRCGERNDES--RIVGGTTTGVSEYPWMARL-SYFNRFYCGGTLINDRYVLTAAHCV 170
            |:|.|       ||:.:.  |||||......|.||.|.| :..|..:||||::|:.|:||||||:
Mouse   230 NETQP-------ERSSDDLVRIVGGRECKDGECPWQALLINEDNEGFCGGTILNEFYILTAAHCL 287

  Fly   171 KGFMWFMIKVTFGEHDRCNDKER-----PETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSF 230
            .....|.::|    .||..:||.     .|...|::  ..||....:|.|||:|||...:.....
Mouse   288 HQARRFKVRV----GDRNTEKEEGNEMVHEVDVVIK--HNKFQRDTYDYDIAVLRLKTPITFRMN 346

  Fly   231 IRPICLPRVEQRQDLFVGTK-AIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMIT 294
            :.|.|||:.:..:...:..| .|.:|:|...|.|:.|.:|:.:|||.:|.:.|...|:::   ||
Mouse   347 VAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCKLSTSFS---IT 408

  Fly   295 KNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQ----IGIVSWGNGCARPNYPGVYTRVTK 355
            :||.|:||. ....|:||||||||.|      .||:.    .||||||.||||....|:||:||.
Mouse   409 QNMFCAGYE-AKLEDACQGDSGGPHV------TRFKNTYYVTGIVSWGEGCARKGKYGIYTKVTT 466

  Fly   356 YLDWI 360
            :|.||
Mouse   467 FLKWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	93/243 (38%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	94/244 (39%)
F10	NP_001229297.1	GLA	36..97	CDD:214503
		EGF_CA	98..134	CDD:238011
		FXa_inhibition	141..176	CDD:291342
		Tryp_SPc	243..471	CDD:214473	93/243 (38%)
		Tryp_SPc	244..473	CDD:238113	94/244 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I3752
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11114
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910