DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and tmprss2.14

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_031752402.1	Gene:	tmprss2.14 / 101731505	XenbaseID:	XB-GENE-22065937	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	94/273 - (34%)
Similarity:	132/273 - (48%)	Gaps:	38/273 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 AAQNQTSPTC-SCRCGERNDESRIVGGTTTGVSEYPWMARLSYFNR-----FYCGGTLINDRYVL 164
            |:.|..|..| ||....:.| |||||||.....::||..:|  ..|     :.|||::|...:|:
Frog   243 ASGNMVSLRCISCGLSTKVD-SRIVGGTVASAGDWPWQVQL--LKRVGASLYLCGGSIITQHWVV 304

  Fly   165 TAAHCVKG-------FMWFMIKVTFGEHDRCN-DKERPETRFVLRAFSQKFSFSNFDNDIALLRL 221
            ||||||.|       |..|...:|...:.... ..||........:::|.:       |:|||:|
Frog   305 TAAHCVYGSTSTPSAFKVFAGSLTIQSYYSAGYTVERALVHPSYSSYTQNY-------DVALLKL 362

  Fly   222 NDRVPITSFIRPICLPRV----EQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDEC 282
            ...:..|:.:||:|||.|    .:.|..::      :||||....|..|..|:...||::.:..|
Frog   363 TAALVFTTNLRPVCLPNVGMPWAEGQPCWI------SGWGTTSNGGSISTNLKAASVPLISSATC 421

  Fly   283 VAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYP 347
            .....| ...|:..|||:||.. ||.|:||||||||||  ...:..:..:|..|||.||...|.|
Frog   422 NQAAVY-GGAISPTMMCAGYLS-GGTDTCQGDSGGPLV--TKTNSLWWLVGDTSWGYGCGMTNKP 482

  Fly   348 GVYTRVTKYLDWI 360
            |||..:|..|:||
Frog   483 GVYGNLTFSLEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	84/249 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	85/250 (34%)
tmprss2.14	XP_031752402.1	LDLa	<96..121	CDD:238060
		LDLa	128..159	CDD:238060
		SRCR_2	164..259	CDD:406055	6/15 (40%)
		Tryp_SPc	265..497	CDD:238113	85/250 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010