DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and tmprss9

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_002940084.3	Gene:	tmprss9 / 100489279	XenbaseID:	XB-GENE-993973	Length:	1151	Species:	Xenopus tropicalis

Alignment Length:	385	Identity:	123/385 - (31%)
Similarity:	174/385 - (45%)	Gaps:	53/385 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RHWPLVLAMASCLLFTAATS--------ATPATPATPATSAPPATSTATSSLSSIPGKYQ--ALG 61
            |..||.::......|..|||        ..|....|.:|.:.|.::|..:|..:...|..  ||.
Frog   793 RSSPLPISTTRPSTFQPATSNGRRTTTLTRPTMSQTKSTRSTPRSTTKYTSKRTTTAKTSPTALR 857

  Fly    62 AAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCGERNDES 126
            .........:....:||:...:..|....|.....|..:.||....||     |.|........:
Frog   858 ITEPARSTQRPVPCSASTYKCSNRVCISKPNPECDGIQDCNNGSDEQN-----CDCGFAPVLPFN 917

  Fly   127 RIVGGTTTGVSEYPWMARLSYFNRFY-CGGTLINDRYVLTAAHCVKGF----MW-------FMIK 179
            :||||:.:...|:||...|....:.: ||..||:||::|:||||...:    :|       |:..
Frog   918 KIVGGSGSVRGEWPWQVSLWLRRKEHKCGAVLISDRWLLSAAHCFDIYSDPKLWAAYLGTPFLNG 982

  Fly   180 VTFGEHDRCNDKERPETRFVLRAFSQKFSFSN---FDNDIALLRLNDRVPITSFIRPICLPRVEQ 241
            |          :.|.|..|.:    .|..|.|   .|||:|||.|...:..|:.|||||||.:..
Frog   983 V----------EGRVEKIFRI----HKHPFYNVYTLDNDVALLELPSPLTYTNLIRPICLPDISH 1033

  Fly   242 RQDLF-VGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGV 305
               :| .||:...||||:.||.|..|..||:..|.::.:..|   ..:....|:..|:|:|:. .
Frog  1034 ---IFPEGTRCFITGWGSTKEGGAMSRQLQKASVSIVGDQTC---KKFYPIQISPRMLCAGFM-Q 1091

  Fly   306 GGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVENSR 365
            ||.|||.||:||||....|..:.| ..||.|||.|||||.:||||||:|...:||.:|.|
Frog  1092 GGVDSCSGDAGGPLACREPSGRWF-LAGITSWGYGCARPYFPGVYTRITSVRNWIGQNLR 1150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	92/248 (37%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	94/250 (38%)
tmprss9	XP_002940084.3	SEA	60..156	CDD:396113
		LDLa	186..221	CDD:238060
		Tryp_SPc	234..463	CDD:214473
		Tryp_SPc	547..774	CDD:238113
		LDLa	871..906	CDD:238060	9/39 (23%)
		Tryp_SPc	919..1145	CDD:238113	92/247 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910