DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4914 and zgc:165423

DIOPT Version :9

Sequence 1:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_005164170.1	Gene:	zgc:165423 / 100101646	ZFINID:	ZDB-GENE-070720-11	Length:	538	Species:	Danio rerio

Alignment Length:	284	Identity:	106/284 - (37%)
Similarity:	146/284 - (51%)	Gaps:	56/284 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 SPTCSCR-------CGERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHC 169
            |..|.|:       ||:....::|||||......:||.|.|......:|||:||:|:::|:||||
Zfish    15 STGCDCQPTQSPPACGKAPLNTKIVGGTNASAGSWPWQASLHESGSHFCGGSLISDQWILSAAHC 79

  Fly   170 VKGFMWFMIKVTFGEHDRCND---------KERPETRFVLRAFSQ-----KFSFSNFDNDIALLR 220
                        |..:...:|         ::.|....|.::.||     .:..|..|||:|||.
Zfish    80 ------------FPSNPNPSDYTVYLGRQSQDLPNPNEVSKSVSQVIVHPLYQGSTHDNDMALLH 132

  Fly   221 LNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDG--KPS-CLLQEVEVPVLDNDEC 282
            |:..|..:::|:|:||   ......|.......|||||: |.|  .|| .:||||.||::.|:.|
Zfish   133 LSSPVTFSNYIQPVCL---AADGSTFYNDTMWITGWGTI-ESGVSLPSPQILQEVNVPIVGNNLC 193

  Fly   283 VAQTNYTQ---KMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFE---QIGIVSWGNGC 341
                |...   ..||.||||:|.. .||:||||||||||:|     .|.|.   |.|:||:|.||
Zfish   194 ----NCLYGGGSSITNNMMCAGLM-QGGKDSCQGDSGGPMV-----IKSFNTWVQAGVVSFGKGC 248

  Fly   342 ARPNYPGVYTRVTKYLDWIVENSR 365
            |.|||||||.||::|.:||.:..|
Zfish   249 ADPNYPGVYARVSQYQNWISQYVR 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	98/255 (38%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	100/257 (39%)
zgc:165423	XP_005164170.1	Tryp_SPc	37..267	CDD:214473	98/255 (38%)
		Tryp_SPc	38..269	CDD:238113	100/256 (39%)
		Tryp_SPc	299..473	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920