Protein Alignment dlp and Gpc2

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_766000.1
• Gene: Gpc2 / 71951
• MGIID: 1919201
• Length: 579
• Species: Mus musculus
• Alignment Length: 682
• Identity: 171/682 - (25%)
• Similarity: 271/682 - (39%)
• Gaps: 139/682 - (20%)

  Fly    31 PLLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAI 95
            |||||||  ||.|.|...:|...:|..                     :|:....:..|||....
Mouse     6 PLLLLLL--HLCPGLGPGHGSEAKVVR---------------------SCAETRQVLGARGYSLN 47

  Fly    96 EIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDI 160
            .||....:...|:.|  |...|||:...|.::...:.....|..:|..|.:...|.::..||.:.
Mouse    48 LIPPSLISGEHLQVC--PQEYTCCSSETEQKLIRDAEVTFRGLVEDSGSFLIHTLAARHRKFNEF 110

  Fly   161 FTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMF 225
            |..:|..|:.....:|..:||.:|.:::.:|:.||..|..|:......|.:.:..|:..|.::.|
Mouse   111 FREMLSISQHSLAQLFSHSYGRLYSQHAVIFNSLFSGLRDYYEKSGEGLDDTLADFWAQLLERAF 175

  Fly   226 TVLNTQYTFDENYMRCVSEHMK----ELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKK 286
            .:|:.||:|..:::.|::....    .|:||||.|.:|.:||.|:.||.|...|.|.|...|..:
Mouse   176 PLLHPQYSFPPDFLLCLTRLTSTADGSLQPFGDSPRRLRLQISRALVAARALVQGLETGRNVVSE 240

  Fly   287 VLNVRLNADCTGALTKMQHCGACKGYTE-KPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVA 350
            .|.|.:...|..||.::..|..|:|... .||..:|:||..|||. ....:.||..:...:..:|
Mouse   241 ALKVPVLEGCRQALMRLIGCPLCRGVPSLMPCRGFCLNVAHGCLS-SRGLEPEWGGYLDGLLLLA 304

  Fly   351 ERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILN 415
            |:|.|.|:..:..|.:.:||||.:|:.|::...::.:|||.||.|
Mouse   305 EKLQGPFSFELAAESIGVKISEGLMHLQENSVKVSAKVFQECGTP-------------------- 349

  Fly   416 ARSPVEADTLDIDETLDEAIVLRERRAAEP---GSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQ 477
              .||::               |.|||..|   .|:...|...:|:....:|..
Mouse   350 --HPVQS---------------RSRRAPAPREEASRSWRASAEEERPTTAAGTN----------- 386

  Fly   478 QQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNED 542
                                              |.|:|.::|:|:...:.||:.||.:||.:..
Mouse   387 ----------------------------------LHRLVWELRERLSRVRGFWAGLPVTVCGDSR 417

  Fly   543 IASS-SDVDGMCWNGHTIDRYMHSIT----TEHGSNPEF-TGNPASTKQTAQMASQLSHLKNAIV 601
            :|:. |.....||.|....|||..:.    .|...|||. |.:|....:..::     ||:.|..
Mouse   418 MAADLSQETAPCWTGVGRGRYMSPVVVGSLNEQLHNPELDTSSPDVPTRRRRL-----HLRAATA 477

  Fly   602 HLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDVERPSVDADND 666
            .::.|..|||::..:.:|       ..||||......||..:|..|..|..:|  .||......|
Mouse   478 RMKAAALGQDLDMHDADE-------DASGSGGGQQYADDWKAGAVPVVPPARP--PRPPRPPRRD 533

  Fly   667 DDEDAGGRGHMPTHTSRPT---SGVDDKNPLI 695
            .....||.|....:..|..   |.|....||:
Mouse   534 GLGVRGGSGSARYNQGRSRNLGSSVGLHTPLV 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	136/553 (25%)
Gpc2	NP_766000.1	Glypican	20..559	CDD:460084	157/658 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	347..382		12/71 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	483..552		21/77 (27%)