Protein Alignment dlp and Gpc6

DIOPT Version :9

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: XP_003751581.1
• Gene: Gpc6 / 691984
• RGDID: 1593308
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 209/602 - (34%)
• Similarity: 304/602 - (50%)
• Gaps: 93/602 - (15%)

  Fly    79 NCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQI 143
            :||.|...:.|:|....:||.:......||.|  |...||||..||.:::.||:.:.|...::..
  Rat    29 SCSEVRQAYGAKGFSLADIPYQEIAGEHLRIC--PQEYTCCTTEMEDKLSQQSKLEFENLVEETS 91

  Fly   144 SRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVD 208
            ..:.....|:..||.:.|..||:.:....|.||:||||::|.:||.||.|||.||:.|:..|.|:
  Rat    92 HFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVN 156

  Fly   209 LLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTY 273
            |.|:::.|:..|.::||.::|.||.|.|:|:.|||::..:||||||||.||.:|:.|:|:|.||:
  Rat   157 LEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTF 221

  Fly   274 GQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGY-TEKPCTNYCVNVIKGCLHYQHEFDS 337
            .|.||...|||.:|..|.....|..||.||.:|..|:|. |.:||.|||:||:||||..|.:.|:
  Rat   222 VQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDT 286

  Fly   338 EWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKR 402
            ||..|..||..|||||.|.|||..|::|:::||||||||.|::...::.:||||||:||.....|
  Rat   287 EWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALR 351

  Fly   403 SISPKLQGVQILNARS-PVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNG 466
            |            ||| |...:|              ..|...|..:.|:|
  Rat   352 S------------ARSAPENFNT--------------RFRPYNPEERPTTA-------------- 376

  Fly   467 GGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWS 531
              .|...:|.:...|..|..                             |.||::::|..||.||
  Rat   377 --AGTSLDRLRTVWRTMQHS-----------------------------VTDIKEKLKLSKKVWS 410

  Fly   532 NLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSI----TTEHGSNPEFTGNPASTKQTAQMASQ 592
            .||:::|.:|.:.:.:..|..|||||:..||:..|    .|...:|||...:  .|:....:..|
  Rat   411 TLPYTICKDERVTAGTSNDEECWNGHSKARYLPEIMNDGLTNQINNPEVEVD--ITRPDTFIRQQ 473

  Fly   593 LSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDVE 657
            :..|:.....|:|||||.||.:.:..:   ..||:|||||..||....|      ||   ....|
  Rat   474 IMALRVMTNKLKNAYNGNDVNFQDTSD---ESSGSGSGSGCMDDVCPTE------FE---FVTTE 526

  Fly   658 RPSVDADNDDDEDAGGR 674
            .|:||.|..::|.:..:
  Rat   527 APAVDPDRREEESSASK 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..613	CDD:279494	190/539 (35%)
Gpc6	XP_003751581.1	Glypican	23..532	CDD:279494	206/589 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	283	1.000	Domainoid score	I1563
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	373	1.000	Inparanoid score	I2042
OMA	1	1.010	-	-		QHG46379
OrthoDB	1	1.010	-	-		D275653at33208
OrthoFinder	1	1.000	-	-		FOG0000903
OrthoInspector	1	1.000	-	-		otm45892
orthoMCL	1	0.900	-	-		OOG6_105830
Panther	1	1.100	-	-	O	PTHR10822
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X519
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.880