Protein Alignment dlp and Gpc1

DIOPT Version :9

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_110455.2
• Gene: Gpc1 / 58920
• RGDID: 61853
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 590
• Identity: 166/590 - (28%)
• Similarity: 263/590 - (44%)
• Gaps: 111/590 - (18%)

  Fly    52 APQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVG 116
            |..:.|.|..:||..          |.:||.|..|:.|:|....::||...:...||.|  |...
  Rat    14 AAALVACARGDPASK----------SRSCSEVRQIYGAKGFSLSDVPQAEISGEHLRIC--PQGY 66

  Fly   117 TCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYG 181
            ||||..||..:|..||.:||....|....:...|.::.....|.|..||.:|.......|...:|
  Rat    67 TCCTSEMEENLANHSRMELETALHDSSRALQATLATQLHGIDDHFQRLLNDSERTLQDAFPGAFG 131

  Fly   182 VIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHM 246
            .:|.:|:..|.||:.||..|:....:.|.|.:.:|:..|.:::|..|:.|....::|:.|:.:..
  Rat   132 DLYTQNTRAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDDYLDCLGKQA 196

  Fly   247 KELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKG 311
            :.|:||||.|.:|.::..|:|||.|::.|.|..||:|.:||..|.|..:|:.|:.|:.:|..|:|
  Rat   197 EALRPFGDAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLAPECSRAVMKLVYCAHCRG 261

  Fly   312 YT-EKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIM 375
            .. .:||.:||.||:||||..|.:.|:||.|...:|..:.::..|......|:..:::.::|||.
  Rat   262 VPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGPSGAENVIGSVHMWLAEAIN 326

  Fly   376 NFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRER 440
            ..||:...:|.:|.||||.||       ::|...|        |.|                 :|
  Rat   327 ALQDNKDTLTAKVIQGCGNPK-------VNPHGSG--------PEE-----------------KR 359

  Fly   441 RAAEPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESG 505
            |..:...||            ||..|
  Rat   360 RRGKLALQE------------KSSTG--------------------------------------- 373

  Fly   506 GGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSITTEH 570
                 .|:::|.:.:.:::|.:.:|.:||.::|| |.:|.|...|..||||.:..||:..:..:.
  Rat   374 -----TLEKLVSEAKAQLRDIQDYWISLPGTLCS-EKMAMSPASDDRCWNGISKGRYLPEVMGDG 432

  Fly   571 GSNPEFTGNPA----STKQTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGS 631
            .:|.  ..||.    .||....:..|:..||.....||.||.|.||::.:..:   .|||:|||.
  Rat   433 LANQ--INNPEVEVDITKPDMTIRQQIMQLKIMTNRLRGAYGGNDVDFQDASD---DGSGSGSGG 492

  Fly   632 GSEDD 636
            |..||
  Rat   493 GCPDD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..613	CDD:279494	150/538 (28%)
Gpc1	NP_110455.2	Glypican	22..539	CDD:395918	163/582 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	478..531		9/23 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341709
Domainoid	1	1.000	283	1.000	Domainoid score	I1563
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	373	1.000	Inparanoid score	I2042
OMA	1	1.010	-	-		QHG46379
OrthoDB	1	1.010	-	-		D275653at33208
OrthoFinder	1	1.000	-	-		FOG0000903
OrthoInspector	1	1.000	-	-		otm45892
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10822
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X519
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910