Protein Alignment dlp and gpc1b

DIOPT Version :9

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_957314.1
• Gene: gpc1b / 393995
• ZFINID: ZDB-GENE-040426-1306
• Length: 541
• Species: Danio rerio
• Alignment Length: 632
• Identity: 170/632 - (26%)
• Similarity: 263/632 - (41%)
• Gaps: 140/632 - (22%)

  Fly    74 DQFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGH 138
            |.....||.:...:..:|.:...:||...:...||.|....  ||||..||..:...||::.|..
Zfish    19 DNKPKTCSDIRLFYSNKGFNLNGVPQTEISGEHLRVCAQGY--TCCTSVMEENLLNLSRREFEMQ 81

  Fly   139 TKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFA 203
            .|:....:...|..:...|.:.|..||..|.....|.|...:|.::.:.|.||.|||.:|..||.
Zfish    82 VKESGRSLQAKLNGQFKSFDEYFLELLNRSEASLQSSFQSGFGSLFSQMSKVFQDLFSDLRRYFR 146

  Fly   204 NGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFV 268
            ...|:|.|.:::|:..|..::|..||.||:..|.|:.||::..::|||||:.|.:|..:|.|:.:
Zfish   147 GSNVNLEEALNEFWARLLDRLFKALNPQYSIGEEYLECVAKQSEKLKPFGETPRELKTKITRTVI 211

  Fly   269 ATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYT-EKPCTNYCVNVIKGCLHYQ 332
            |.||:.|.|..:.|..:||..|.|:.:|..|:.|..:|..|.|.. .|||:|||.||:||||..|
Zfish   212 AARTFVQGLVISGEAVRKVSQVSLSTECVRAVMKQTYCPHCSGVALAKPCSNYCRNVLKGCLANQ 276

  Fly   333 HEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKL 397
            .:.|:||.|.|.||.:|.::|...:::..||..|..:|:|||:..||:.....|:||..||.|
Zfish   277 ADLDTEWRNLADAMLEVVDKLSRPYSVDSVVLSLPKRIAEAILYMQDNQDMFINKVFLECGTP-- 339

  Fly   398 KKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGK 462
                                    |.:.:|.|.     :.|.|..||..|....||
Zfish   340 ------------------------APSSNIQEQ-----IKRGRNTAEEVSSTPGAQ--------- 366

  Fly   463 SGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYK 527
                                                             |:|::.|:.:.::|..
Zfish   367 -------------------------------------------------LERLLSDVSRMLRDMM 382

  Fly   528 KFWSNLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSITTEHGSNPEFTG--------NPA--- 581
            ::|.:||..:|.:.:  |.......||||.::.||:          ||..|        ||.
Zfish   383 QYWVHLPRKLCVDRE--SGPGESDRCWNGMSVGRYL----------PEVMGDGLASQINNPEVEI 435

  Fly   582 -STKQTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGL 645
             .||....:..|:..||..|..|:.|.||.||::.:..:     ..:|||||...|:....|..|
Zfish   436 DITKPDMAVRKQIMQLKIMINRLKYAVNGNDVDFQDTSD-----DISGSGSGMCLDDQCSRGPRL 495

  Fly   646 GPFEPSHKPDVERPSVDADNDDDEDAGGRGHMPTHTSRPTSGVDDKN 692
                  ..|:.::|.|.|.             |:...:..:|...:|
Zfish   496 ------MSPNTDKPKVYAS-------------PSENKKVVNGRSSQN 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..613	CDD:279494	153/546 (28%)
gpc1b	NP_957314.1	Glypican	6..538	CDD:279494	170/632 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581724
Domainoid	1	1.000	278	1.000	Domainoid score	I1678
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	353	1.000	Inparanoid score	I2219
OMA	1	1.010	-	-		QHG46379
OrthoDB	1	1.010	-	-		D275653at33208
OrthoFinder	1	1.000	-	-		FOG0000903
OrthoInspector	1	1.000	-	-		otm24302
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10822
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X519
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.870