Protein Alignment dlp and gpn-1

DIOPT Version :9

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_510582.1
• Gene: gpn-1 / 181658
• WormBaseID: WBGene00001687
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 127/549 - (23%)
• Similarity: 231/549 - (42%)
• Gaps: 123/549 - (22%)

  Fly   116 GTCCTYNMETRMAMQSRQQLEGHTKDQISR--------MSGILGSKATKFKDIFTALLKESRTQF 172
            |..|:.:.|.:..|:.|.:|:.:|.|.::|        :...|.|:...|.:.|:..|:......
 Worm    32 GVMCSSSFEDQCTMEERSRLQTNTVDMLTRKHQDRVIVIRSFLTSQIRIFNEFFSKTLRTVHMDL 96

  Fly   173 NSMFIRTYGVIYERNSYVFSDLFKELETYFAN-GRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDE 236
            :.||.:|||..|:.|..:.:|.||:::.:..: ....:..:::.||:.|:|.||::.|..|:...
 Worm    97 DLMFSKTYGSFYQENIQLLNDFFKKIKGFSVSFAETSMKTIVELFFDELFQVMFSIANPFYSITN 161

  Fly   237 NYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALT 301
            :...|:....:|::.|.|:|.|:..|:.......:.:..:|.:.:.:.:..||:....:|...||
 Worm   162 DQRVCMESFYREIEAFDDIPQKIVNQLSLPLSNWKHFLGSLESLNGILEGYLNITFKEECERGLT 226

  Fly   302 KMQHCGACKGYTEKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPL 366
            :|:.|..|:..:||||..||||::.||.|...:.:..|.....:|.|:..:|....|:|..::|:
 Worm   227 RMETCAQCQRISEKPCQAYCVNILSGCTHQMLDSEGAWRAATESMIKLGNQLNHRQNLVSALQPI 291

  Fly   367 NIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETL 431
            .:.||||||:||:....|||::...|                    :||
 Worm   292 PVLISEAIMHFQEKRDYITNKMIGKC--------------------LLN---------------- 320

  Fly   432 DEAIVLRERRAAE-PGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRD 495
            :|...||::|:|: ......:.::|::
 Worm   321 NEDFGLRKKRSAKFKAFPVITTKRSRD-------------------------------------- 347

  Fly   496 DNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGHTID 560
                         ..||:::.:....::.::|.|:.|||..:|..||.||..  |..||||..:.
 Worm   348 -------------HLILNQMFQSFANKMDEWKVFFGNLPEYLCRGEDWASKE--DERCWNGTGVG 397

  Fly   561 RYMHSIT--TEHGSNPEFTGNPASTKQTAQMASQLS-H-LKNAIVHLRNAYNGQ----------- 610
            .|...:.  |...||||:.|....|.:...:..:|. | |.:.|.|:.:..:.|
 Worm   398 EYKLPLVNYTNPFSNPEYQGTDFLTFRGNYIEERLRLHWLHSRISHILSGKDSQKSEAYYSHKAE 462

  Fly   611 ------DVEWSEQEELPYAGSGAGSGSGS 633
                  |.::|:.|   |..||...||||
 Worm   463 ARIQSDDEDYSDYE---YESSGNFPGSGS 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..613	CDD:279494	118/527 (22%)
gpn-1	NP_510582.1	Glypican	43..>414	CDD:279494	104/459 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159808
Domainoid	1	1.000	155	1.000	Domainoid score	I2593
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55582
Inparanoid	1	1.050	208	1.000	Inparanoid score	I2393
Isobase	1	0.950	-	0	Normalized mean entropy	S6660
OMA	1	1.010	-	-		QHG46379
OrthoDB	1	1.010	-	-		D275653at33208
OrthoFinder	1	1.000	-	-		FOG0000903
OrthoInspector	1	1.000	-	-		oto19962
orthoMCL	1	0.900	-	-		OOG6_105830
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3318
SonicParanoid	1	1.000	-	-		X519
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.690