Protein Alignment dlp and Gpc2

DIOPT Version :9

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_612520.1
• Gene: Gpc2 / 171517
• RGDID: 621363
• Length: 579
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 167/656 - (25%)
• Similarity: 270/656 - (41%)
• Gaps: 130/656 - (19%)

  Fly    31 PLLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAI 95
            |||||||.  |.|      ||.|           |..:.:.::    .:|:....:..|||....
  Rat     6 PLLLLLLP--LCP------GPGP-----------GHGSEAKVV----RSCAETRQVLGARGYSLN 47

  Fly    96 EIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDI 160
            .||....:...|:.|  |...|||:...|.::...:.....|..:|..|.:...|.::..||.:.
  Rat    48 LIPPSLISGEHLQIC--PQEYTCCSSETEQKLIRDAEVTFRGLVEDSGSFLIHTLAARHRKFNEF 110

  Fly   161 FTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMF 225
            |..:|..|:.....:|..:||.:|.:::.:|:.||..|..|:......|.:.:..|:..|.::.|
  Rat   111 FREMLSISQHSLAQLFSHSYGRLYSQHAVIFNSLFSGLRDYYEKSGEGLDDTLADFWAQLLERAF 175

  Fly   226 TVLNTQYTFDENYMRCVSEHMK----ELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKK 286
            .:|:.||:|..:::.|::....    .|:||||.|.:|.:||.|:.||.|...|.|.|...|..:
  Rat   176 PLLHPQYSFPPDFLLCLTRLTSTADGSLQPFGDSPRRLRLQITRALVAARALVQGLETGRNVVSE 240

  Fly   287 VLNVRLNADCTGALTKMQHCGACKGYTE-KPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVA 350
            .|.|.:...|..||.::..|..|:|... .||..:|:||..|||. ....:.||..:...:..:|
  Rat   241 ALKVPMLEGCRQALMRLIGCPLCRGVPSLMPCRGFCLNVAHGCLS-SRGLEPEWGGYLDGLLLLA 304

  Fly   351 ERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILN 415
            |:|.|.|:..:..|.:.:||||.:|:.|::...::.:|||.||.|
  Rat   305 EKLQGPFSFELAAESIGVKISEGLMHLQENSVKVSAKVFQECGTP-------------------- 349

  Fly   416 ARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQR 480
              .||::               |.|||..| .:|||
  Rat   350 --HPVQS---------------RNRRAPAP-REETS----------------------------- 367

  Fly   481 RKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIAS 545
                      ::.|...:::...:..|..  |.|:|.::|:|:...:.||:.||.:||.:..:|:
  Rat   368 ----------RSWRSSAEEERPTTAAGTN--LHRLVWELRERLSRVRGFWAGLPVTVCGDSRMAA 420

  Fly   546 S-SDVDGMCWNGHTIDRYMHSIT----TEHGSNPEF-TGNPASTKQTAQMASQLSHLKNAIVHLR 604
            . |.....||.|....|||..:.    .|...|||. |.:|....:..::     ||:.|...::
  Rat   421 DLSQEAAPCWTGVGRGRYMSPVVVGSLNEQLHNPELDTSSPDVPTRRRRL-----HLRAATARMK 480

  Fly   605 NAYNGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDVERPSVDADNDDDE 669
            .|..|||::..:.:|       ..||||......||..:|..|..|..:|  .||......|...
  Rat   481 AAALGQDLDMHDADE-------DASGSGGGQQYADDWKAGAAPVVPPARP--PRPPRPPRRDGLG 536

  Fly   670 DAGGRG 675
            ..||.|
  Rat   537 VRGGSG 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..613	CDD:279494	137/544 (25%)
Gpc2	NP_612520.1	Glypican	22..565	CDD:279494	154/621 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	347..382		13/111 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	483..552		20/69 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341710
Domainoid	1	1.000	283	1.000	Domainoid score	I1563
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	373	1.000	Inparanoid score	I2042
OMA	1	1.010	-	-		QHG46379
OrthoDB	1	1.010	-	-		D275653at33208
OrthoFinder	1	1.000	-	-		FOG0000903
OrthoInspector	1	1.000	-	-		otm45892
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10822
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X519
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.870