Protein Alignment dlp and Gpc3

DIOPT Version :9

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_057906.2
• Gene: Gpc3 / 14734
• MGIID: 104903
• Length: 579
• Species: Mus musculus
• Alignment Length: 595
• Identity: 125/595 - (21%)
• Similarity: 232/595 - (38%)
• Gaps: 124/595 - (20%)

  Fly    69 GSSIIDQFSP------NCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRM 127
            |...:.|..|      .|..|...||........:|:.|.....|:.| .|...|||:..||.:.
Mouse    17 GLGCLGQAQPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVC-LPKGPTCCSRKMEEKY 80

  Fly   128 AMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFS 192
            .:.:|..:|...:.....:..::...|..|::.|..:::.::...|:||...|..:..:......
Mouse    81 QLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVG 145

  Fly   193 DLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQY--------TFDENYMRCVSEHMKEL 249
            :.|.::..|.....::    :|...|.|:..:|.|:.||.        ..|.|  .|:....::|
Mouse   146 EFFTDVSLYILGSDIN----VDDMVNELFDSLFPVIYTQMMNPGLPESVLDIN--ECLRGARRDL 204

  Fly   250 KPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKG-YT 313
            |.||..|..:..|:.:|...||.:.|||....||.....:::.:.||...||:|.:|..|:| ..
Mouse   205 KVFGSFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMM 269

  Fly   314 EKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQ 378
            .|||..||..|::||:....|.|..|..:.::::::...:...:::..|:..|...|.::|...|
Mouse   270 VKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQ 334

  Fly   379 DSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAA 443
            .:|..:|..:.:.|...:.::.:.:..|:                    |..:|:.|:    :.|
Mouse   335 KNGGKLTTTIGKLCAHSQQRQYRSAYYPE--------------------DLFIDKKIL----KVA 375

  Fly   444 EPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGR 508
            ....:||.                     ::||
Mouse   376 HVEHEETL---------------------SSRR-------------------------------- 387

  Fly   509 EPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNG-HTIDRYMHSITTEHGS 572
                    |::.|::|.:..|:|.||..:||:..:|.:   |.:|||| ..::||... ...:|.
Mouse   388 --------RELIQKLKSFINFYSALPGYICSHSPVAEN---DTLCWNGQELVERYSQK-AARNGM 440

  Fly   573 NPEFTGNPASTK----QTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGS 633
            ..:|..:....|    ..:|:..:|.|: |.::...:...|:.::.|..||      |..||. .
Mouse   441 KNQFNLHELKMKGPEPVVSQIIDKLKHI-NQLLRTMSVPKGKVLDKSLDEE------GLESGD-C 497

  Fly   634 EDDEDDDEGS 643
            .||||:..||
Mouse   498 GDDEDECIGS 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..613	CDD:279494	110/547 (20%)
Gpc3	NP_057906.2	Glypican	14..576	CDD:279494	125/595 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	533..552

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3821
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810