Protein Alignment dlp and Gpc1

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_057905.1
• Gene: Gpc1 / 14733
• MGIID: 1194891
• Length: 557
• Species: Mus musculus
• Alignment Length: 565
• Identity: 159/565 - (28%)
• Similarity: 253/565 - (44%)
• Gaps: 102/565 - (18%)

  Fly    77 SPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKD 141
            |.:||.|..|:.|:|....::||...:...||.|  |...||||..||..:|..||.:||....|
Mouse    29 SRSCSEVRQIYGAKGFSLSDVPQAEISGEHLRIC--PQGYTCCTSEMEENLANHSRMELESALHD 91

  Fly   142 QISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGR 206
            ....:...|.::.....|.|..||.:|.......|...:|.:|.:|:..|.||:.||..|:....
Mouse    92 SSRALQATLATQLHGIDDHFQRLLNDSERTLQEAFPGAFGDLYTQNTRAFRDLYAELRLYYRGAN 156

  Fly   207 VDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATR 271
            :.|.|.:.:|:..|.:::|..|:.|...|: |:.|:.:..:.|:||||.|.:|.::..|:|||.|
Mouse   157 LHLEETLAEFWARLLERLFKQLHPQLLPDD-YLDCLGKQAEALRPFGDAPRELRLRATRAFVAAR 220

  Fly   272 TYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYT-EKPCTNYCVNVIKGCLHYQHEF 335
            ::.|.|..||:|.:||..|.|..:|:.|:.|:.:|..|:|.. .:||.:||.||:||||..|.:.
Mouse   221 SFVQGLGVASDVVRKVAQVPLAPECSRAIMKLVYCAHCRGVPGARPCPDYCRNVLKGCLANQADL 285

  Fly   336 DSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKM 400
            |:||.|...:|..:.::..|......|:..:::.::|||...||:...:|.:|.|.||.||:
Mouse   286 DAEWRNLLDSMVLITDKFWGPSGAESVIGGVHVWLAEAINALQDNKDTLTAKVIQACGNPKV--- 347

  Fly   401 KRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGN 465
                                                                            |
Mouse   348 ----------------------------------------------------------------N 348

  Fly   466 GGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFW 530
            ..|.|....||:.:...|::                 .|.|    .|:::|.:.:.:::|.:.||
Mouse   349 PHGSGPEEKRRRGKLALQEK-----------------PSTG----TLEKLVSEAKAQLRDIQDFW 392

  Fly   531 SNLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSI----TTEHGSNPEFTGNPASTKQTAQMAS 591
            .:||.::|| |.:|.|...|..||||.:..||:..:    .....:|||...:  .||....:..
Mouse   393 ISLPGTLCS-EKMAMSPASDDRCWNGISKGRYLPEVMGDGLANQINNPEVEVD--ITKPDMTIRQ 454

  Fly   592 QLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSEDD 636
            |:..||.....||.||.|.||::.:..:   .|||:|||.|..||
Mouse   455 QIMQLKIMTNRLRGAYGGNDVDFQDASD---DGSGSGSGGGCPDD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	149/544 (27%)
Gpc1	NP_057905.1	Glypican	22..538	CDD:460084	159/565 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	477..531		9/23 (39%)