Protein Alignment dlp and gpc4

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_571935.2
• Gene: gpc4 / 118437
• ZFINID: ZDB-GENE-011119-1
• Length: 557
• Species: Danio rerio
• Alignment Length: 617
• Identity: 199/617 - (32%)
• Similarity: 299/617 - (48%)
• Gaps: 124/617 - (20%)

  Fly    67 VAGSSIIDQFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQS 131
            |..|:..||.|.||:.|...:.::|.:..::|.|......|:.|  |...:|||..||.:::..|
Zfish    15 VLASAQADQKSKNCNEVRTAYSSKGFNVNDVPNKGVQGAHLKVC--PQGFSCCTLEMEEKLSQLS 77

  Fly   132 RQQLEGHTKDQISRMSGILGSKATK----FKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFS 192
            |..|    |..:.::|..|.|..|:    |...|..||..:....|.||:||||::|.:|..:|.
Zfish    78 RVDL----KVPVHQLSSNLQSTFTQRHRHFDQFFRELLDNAEKSLNHMFVRTYGLMYVKNKELFE 138

  Fly   193 DLFKELETYFANG--RVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDV 255
            ..|.:|..|:::|  .|:|.:::.:|::.|.::||.::|.||.|.::||.|||.|..:|||||||
Zfish   139 GFFSDLRRYYSHGSSEVNLDDMLAEFWSELLERMFRLVNVQYEFSDSYMECVSRHTDQLKPFGDV 203

  Fly   256 PDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYTE-KPCTN 319
            |.||.:|:.|||:|.|.:.:.||...:|.:||..|..:..|..|..||.:|..|.|... |||.|
Zfish   204 PRKLRLQLTRSFIAVRAFTRGLTLMPDVVRKVSTVSASPSCVRASMKMLYCPYCSGQVALKPCKN 268

  Fly   320 YCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDI 384
            ||:||::|||..|.:.|:||.||..:|..:||||.|.||...||:|:::|||:||||.|::...:
Zfish   269 YCLNVMRGCLANQADLDTEWNNFLDSMLGLAERLEGPFNFESVVDPIDVKISDAIMNMQENSMQV 333

  Fly   385 TNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAE----P 445
            :.:||||||:|||                                    ::..|.||:|:    |
Zfish   334 SQKVFQGCGQPKL------------------------------------SMGFRSRRSAKDSGFP 362

  Fly   446 GS-QETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGRE 509
            |. :..|.:.......|.:
Zfish   363 GRFRPYSPEARPTTAAGTT---------------------------------------------- 381

  Fly   510 PILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSITTEHG--- 571
              |||::.|:::::|..|||||.||.:||..|.||.|.|    ||||....|| .|:....|
Zfish   382 --LDRLLTDVKKKLKHAKKFWSTLPDTVCVGERIAPSDD----CWNGTAKSRY-ESVVMSSGLAN 439

  Fly   572 --SNPEFTGNPASTKQTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSE 634
              |||:...:  .||....:..|::.||.....|:.||.|.|:.::..:    ||||..||||.:
Zfish   440 QVSNPDVEVD--ITKPDMVIRRQIAVLKEMTSWLKAAYTGNDISFTSDD----AGSGEESGSGCD 498

  Fly   635 DDEDDDEG----SGLGPFEPS--HKPDVERPS 660
            ....:.:|    |...|.:|.  ..|:||:.|
Zfish   499 SPSCEGDGDIYFSTPAPGKPRILKTPEVEQAS 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	178/556 (32%)
gpc4	NP_571935.2	Glypican	9..538	CDD:460084	199/617 (32%)