Protein Alignment dlp and Gpc5

DIOPT Version :10

• Sequence 1: NP_524071.2
• Gene: dlp / 39596
• FlyBaseID: FBgn0041604
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: XP_036014229.1
• Gene: Gpc5 / 103978
• MGIID: 1194894
• Length: 626
• Species: Mus musculus
• Alignment Length: 664
• Identity: 145/664 - (21%)
• Similarity: 269/664 - (40%)
• Gaps: 150/664 - (22%)

  Fly    39 THLPPTLQADNGPAPQVAALAAPNPAG-GVAGSSIID----------------------QFSPNC 80
            |||||.|       |.:.||.:.:.:| |...:..:|                      :...:|
Mouse    46 THLPPAL-------PMLGALESEDHSGEGATRTPRMDARTWRLGWRCLLLLALLGSTRSEGVESC 103

  Fly    81 SAVTHIFQARGIDAIE-IPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQIS 144
            ..|..:||.|...|:: :|:.|.....|:.|.|.: .||||..||.|..:.:||.|:...:...|
Mouse   104 EEVRKLFQWRLGGAVKGLPEAPRAGPDLQVCLSKN-PTCCTRKMEERYQIAARQDLQQVLQTSSS 167

  Fly   145 RMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDL 209
            .:..::...|..|::....|::::....:.:|..||..:....:....:.|.::..|.....|:.
Mouse   168 TLKLLISRNAAAFQETLETLIRQAENYTSILFCNTYRNMALEAAASIQEFFTDVGLYLFGADVNP 232

  Fly   210 LEVMDKFFNTLYQKMFTVLNTQYTFDEN--YMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRT 272
            .|.:::||::|:..::..|......|.:  |..|:....:::.|||::|.::..|:.||.:..||
Mouse   233 EEFVNRFFDSLFPLVYNHLINPGVTDSSLQYSECIRMARQDVSPFGNIPKRVMGQMGRSLLPGRT 297

  Fly   273 YGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKG-YTEKPCTNYCVNVIKGCLHYQHEFD 336
            :.|||....||.....::..:.:|:.||.|||:|..|:. ...|||..||:|||:|||.:..|.:
Mouse   298 FLQALNLGIEVINTTDHIHFSKECSRALLKMQYCPHCQSLMLSKPCMGYCLNVIRGCLAHMTELN 362

  Fly   337 SEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMK 401
            ..|..:..:::::::.:.|::::..|:...::.:::|::....:||.:.::|...||.|
Mouse   363 PHWHAYIRSLEELSDAMHGTYDVEHVLLNFHLLVNDAVLQAHLNGQKLLDQVNTICGHP------ 421

  Fly   402 RSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNG 466
                          .|:|.::.....|.            :.|....:.||:..:|...
Mouse   422 --------------VRTPTQSPRCTFDP------------SKEKHGMKISARNGEETLA------ 454

  Fly   467 GGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWS 531
                   |||::                                    .:..:|.    :..|:.
Mouse   455 -------NRRKE------------------------------------FINSLRL----HGSFYG 472

  Fly   532 NLPHSVCSNEDIASSSDVDGM-CWNGHTI-----DRYMHSITTEHGSNPEFTGNPASTKQTAQMA 590
            .|...:|.||..|.    :|. ||||..|     .|.:.:......:|||     ...:.|..:.
Mouse   473 GLADQLCVNELAAP----EGRPCWNGEEIVKSYAQRVVGNGIKAQSANPE-----VRVRGTDPVV 528

  Fly   591 SQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAG---SGSGSEDDEDDDEGSGLGPFEPS- 651
            :|:......::.|....:.:..:|    ||...|||.|   :.||..||||...|||.|..:.:
Mouse   529 NQIIDKLKHVIQLLRGRSPKPNKW----ELLQPGSGGGMLENSSGDCDDEDGCGGSGSGEVKRTL 589

  Fly   652 -------HKPDVER 658
                   ||..:|:
Mouse   590 KITNFSCHKTSLEK 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlp	NP_524071.2	Glypican	79..619	CDD:460084	114/549 (21%)
Gpc5	XP_036014229.1	Glypican	93..592	CDD:460084	130/597 (22%)