Protein Alignment RecQ5 and Recql

DIOPT Version :9

• Sequence 1: NP_729983.1
• Gene: RecQ5 / 39594
• FlyBaseID: FBgn0027375
• Length: 1058
• Species: Drosophila melanogaster
• Sequence 2: NP_001342440.1
• Gene: Recql / 19691
• MGIID: 103021
• Length: 648
• Species: Mus musculus
• Alignment Length: 643
• Identity: 187/643 - (29%)
• Similarity: 299/643 - (46%)
• Gaps: 125/643 - (19%)

  Fly     7 VHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITIVFSPL 71
            |.:.|:..|...||: .||.:.:...:.:| |:::.||||.|||||:|||.|.|:. .|:|..||
Mouse    79 VKDVLQNVFKLQKFR-PLQLETINVTMARK-DIFLVMPTGGGKSLCYQLPALCSDG-FTLVICPL 140

  Fly    72 LALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTNLKFLYITPEQ-AATKFFQDLLQ 135
            ::|::||:..|.:|.:.|..||:..|.:....|..::....:.||.:|:|||: |.:|.|...|:
Mouse   141 ISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSQLKLIYVTPEKIAKSKMFMSRLE 205

  Fly   136 TLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDIYKQLR 200
            ..::..:|...||||.||.|||||||||||..||.|:.::.:...:.|||||:..|.:|:.|.|.
Mouse   206 KAYEAGRLTGAAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLMGLTATATNHVLKDVQKILC 270

  Fly   201 LHQPVAQFSTPSF-RKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEFKDTPKPQRGCGIVYCR 264
            :.:.:.  .|.|| |.||||::..|.|..:||..  |..:...|..|         ...||:||.
Mouse   271 VGKCLT--FTASFNRPNLFYEVRQKPSSAEDFTE--DIVKLINGRYK---------GQSGIIYCF 322

  Fly   265 TRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFVI 329
            ::...|::.|.:.|.||.|..|||.::..::|:|...|...:..::.||.:||||:|||.|||||
Mouse   323 SQKDSEQITISLQKLGIHAGTYHANMEPEDKTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVI 387

  Fly   330 HWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSI--RFLLQNDAHRARGRGDKELLTERA 392
            |..:.:::..|||||||||||..::.|.||||..|:..|  ..:::|...:
Mouse   388 HHSMSKSMENYYQESGRAGRDDSRADCILYYGFGDIFRISSMVVMENVGQQ-------------- 438

  Fly   393 IKQFEKITEFCERTT-CRHKLFSDFFGD--PTPDCSGQCDVCKRPKKAEKALEIFHRLCMDDAFK 454
             |.:|.:: :|:..: ||..|.:..|.:  ....|:..||.|                |.|.:|:
Mouse   439 -KLYEMVS-YCQNVSKCRRVLIAQHFDEVWNADACNKMCDNC----------------CKDVSFE 485

  Fly   455 SHISLQDCADLYEGGRPGIKRAAQEYAGGESGSDDDSGQSHSSMAKRAKKESQDFIKQQFNLRKQ 519
            .....|.|.||.:                                         .:||...|.::
Mouse   486 KKNVTQHCRDLIK-----------------------------------------ILKQAEGLNEK 509

  Fly   520 ISAARQLEQETIAQISRVRMA---------EATEKKIAG--LQATHREKY---LTALIDALKANV 570
            ::..:.::.......:::|:|         |..|:.:|.  ||...:|.|   ..|.|..||..
Mouse   510 LTPLKLIDAWMGKGAAKLRVAGVVAPALPREDLERIVAHALLQQYLKEDYSFTAYATISYLKVG- 573

  Fly   571 DKCKDEPGQQPKSVLKYNDYEAMSVNMEYDVFRQNKVANMYRHALVKEISTIKKLTEQ 628
                      |::.|..|  ||.:|.|:.....|:.|......|  :::..:....|:
Mouse   574 ----------PRACLLSN--EAHAVTMQVKKSAQSSVRGALSEA--RQVEQVDSKGEE 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RecQ5	NP_729983.1	RecQ	6..>442	CDD:223588	153/441 (35%)
		DEAD	37..193	CDD:278688	66/156 (42%)
		HELICc	<257..359	CDD:238034	43/101 (43%)
		RecQ_Zn_bind	364..431	CDD:292742	13/71 (18%)
Recql	NP_001342440.1	recQ_fam	81..543	CDD:129701	165/550 (30%)
		DEVH box	219..222		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	601..648		2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0514
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R580
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840