Protein Alignment RecQ5 and Blm

DIOPT Version :10

• Sequence 1: NP_729983.1
• Gene: RecQ5 / 39594
• FlyBaseID: FBgn0027375
• Length: 1058
• Species: Drosophila melanogaster
• Sequence 2: XP_061506564.1
• Gene: Blm / 1272996
• VectorBaseID: AGAMI1_000433
• Length: 1481
• Species: Anopheles gambiae
• Alignment Length: 799
• Identity: 226/799 - (28%)
• Similarity: 358/799 - (44%)
• Gaps: 167/799 - (20%)

  Fly     2 AHESAVHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITI 66
            ||.:.:..|.|:.||...|: .:|.:.:. |.....|.:|.||||.|||||:|||.:::.. :||
Mosquito   693 AHSARLQVAFKETFGLRTFR-PIQLQVIN-ATLLGNDCFVLMPTGGGKSLCYQLPAVLTVG-LTI 754

  Fly    67 VFSPLLALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTNLKFLYITPEQ-AATKFF 130
            |.|||.:||.||:..|..|.:||..|:.:.:..:..|:..||.:....||.||:|||: :::..|
Mosquito   755 VVSPLKSLILDQVQKLNSLDIPAGHLSGEANMADVQRIYDDLYSSCPELKLLYVTPEKISSSAKF 819

  Fly   131 QDLLQTLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDI 195
            |:||..|::.:.|....:|||||||.|||||||||.||..||.::..|..:||||||:..|:.||
Mosquito   820 QNLLSALYRRSLLGRIVIDEAHCVSAWGHDFRPDYKKLSALREQFPTVPIIALTATANPRVRMDI 884

  Fly   196 YKQLRLHQPVAQFSTPSFRKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEF-KDTPKPQRGCG 259
            ..||:|.:....|.....|.||.|.::.|..:....: :.:..|      |.| :||       |
Mosquito   885 LAQLKLARDTRWFLCSFNRPNLKYLVLPKKGVSTKAE-MIELIR------KRFPRDT-------G 935

  Fly   260 IVYCRTRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQ-PIICATNSFGMGVDKP 323
            ||||.::.:.:::|....:.||.|.:|||||..|.|...|:.|: ||: .::|||.:||||:|||
Mosquito   936 IVYCLSKKECDQLADEFRRAGIKAKSYHAGLSDGVREATQKEWI-GDRIKVVCATIAFGMGIDKP 999

  Fly   324 SVRFVIHWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSIRFLLQNDAHRARGRGDKELL 388
            .||:|:|:.:|:::..||||||||||||..:.|.|||...|:...|.::.||...:        |
Mosquito  1000 DVRYVLHYCMPKSIEGYYQESGRAGRDGEIATCVLYYNYSDMLRYRKMMDNDTSIS--------L 1056

  Fly   389 TERAI--KQFEKITEFCERTT-CRH----KLFSDFFGDPTPDCSGQCDVCKRPKKAEKALEIFHR 446
            ..:.|  ....::..:||..| ||.    :.|:::|      .|.|| :..|....:..|:
Mosquito  1057 EAKQIHMNNLFRMVNYCENVTDCRRTQQLEYFAEYF------TSEQC-LANRETACDNCLQ---- 1110

  Fly   447 LCMDDAFKSHISLQDCADLYEGGRPGIKRAAQEYAGGESGSDDDSGQSHSSMAKRAKKESQDFIK 511
               ...:|:.....||.        .|.:|.::..||                           :
Mosquito  1111 ---QGNYKTLNVTDDCI--------MIAKAVRDLCGG---------------------------R 1137

  Fly   512 QQFNLRKQISAARQLEQETIAQISRVRMAEATEKKIAGLQATHREKYLTALIDALKANVDKCKDE 576
            .:|.|...:...:..|                .||:  |:..|..   ||....||| .::|..
Mosquito  1138 NRFTLLHMVEVLKGSE----------------NKKV--LENGHNR---TAYHGKLKA-WERCDI- 1179

  Fly   577 PGQQPKSVLKYNDYEAMSVNMEYDVFRQNKVANMYRHALVKEISTIKKLTEQTKLLPLLVDYIPK 641
              |:....|..::|      ::.|:...|.:...|.....|..|.:.:...        |::..|
Mosquito  1180 --QRLLRKLVIDEY------LKEDLIFSNDIPQAYLRIGTKIESLVSRRVR--------VEFSIK 1228

  Fly   642 PETSSKGAWTG---GSVA----------YFERKLKELEEQRPQSLKEVPKALKDRKGFKQENSKQ 693
            .:.:.:|..||   |.||          ....:||:|:.:....|.|:.:|:.     .|:|:..
Mosquito  1229 EKHAGRGKLTGRAAGDVAAAAAAQQESTQIGAQLKDLQTRCYNDLLEICRAIA-----MQKNATL 1288

  Fly   694 TSISSF-----FKKEIKEEPID----------------SPIQEERVNIKSEQ----MDLEESTPK 733
            .||.:.     ..:::.|.|.:                ..:.|...|..:|:    ||.::...:
Mosquito  1289 ASIMNIQALKAMSEKLPESPAEMLTLPHVTKANFEKYGKQLLEITQNYAAEKLMLMMDTQDQEEQ 1353

  Fly   734 DIASNHVKEESVTPESSSS 752
            ..|...|..||...:..||
Mosquito  1354 GAAVTLVDGESGDSDGGSS 1372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RecQ5	NP_729983.1	RecQ	5..447	CDD:440280	165/451 (37%)
		SMC_N	658..>963	CDD:481474	23/120 (19%)
Blm	XP_061506564.1	None