Protein Alignment RecQ5 and recql5

DIOPT Version :9

• Sequence 1: NP_729983.1
• Gene: RecQ5 / 39594
• FlyBaseID: FBgn0027375
• Length: 1058
• Species: Drosophila melanogaster
• Sequence 2: XP_031749855.1
• Gene: recql5 / 100216093
• XenbaseID: XB-GENE-958080
• Length: 1071
• Species: Xenopus tropicalis
• Alignment Length: 1126
• Identity: 366/1126 - (32%)
• Similarity: 542/1126 - (48%)
• Gaps: 249/1126 - (22%)

  Fly     7 VHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITIVFSPL 71
            :...||..||.:.|:|||||.|.:..||.:.||:|.||||:|||||:|||.::|.. ||:|.|||
 Frog    38 IQTTLKNVFGFNSFRSDLQENATRAVVKGETDVFVVMPTGAGKSLCYQLPAVLSVG-ITVVISPL 101

  Fly    72 LALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTNLKFLYITPEQAATKFFQDLLQT 136
            :|||:||:|||..||:.|.|||||:...||.::|.||::....:|.||||||.||:..||.:|..
 Frog   102 IALIQDQVDHLVALKIKACSLNSKLPLPERKKIIQDLESEAPQIKLLYITPEMAASASFQPILAQ 166

  Fly   137 LHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDIYKQLRL 201
            |...:.|:|..:|||||||:||||||||||:||.|||:......:||||||:::|::||...|:|
 Frog   167 LLSRSLLSYLIIDEAHCVSEWGHDFRPDYLRLGSLRSRIPHTPCVALTATATKQVQDDIIASLKL 231

  Fly   202 HQPVAQFSTPSFRKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEFKDTPKPQ---RGCGIVYC 263
            .|||:.|.||.||.|||||:..|:.:.|.:..|.:|....||       |..||   .|||||||
 Frog   232 RQPVSMFKTPCFRSNLFYDVQLKDLVGDPYGDLKEFCLKALG-------TKTPQGGFPGCGIVYC 289

  Fly   264 RTRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFV 328
            ||||..|.:|:.::::|:.:..||||||.|:|..:|..||.|..|:|.||.||||||||.:||||
 Frog   290 RTRDACEEVAVQLSQRGVLSKPYHAGLKAGDRVTIQNDWMDGTVPVIVATISFGMGVDKANVRFV 354

  Fly   329 IHWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSIRFLLQNDAHRARG-RGDKELLTERA 392
            .||::.:::|.||||||||||||.|::|||||.|.|...:.||::.:..:|:. |||.:...:..
 Frog   355 AHWNIAKSLAGYYQESGRAGRDGKQAFCRLYYSRTDRDQVGFLIRKEIAQAQAKRGDNKASDKAG 419

  Fly   393 IKQFEKITEFCERTTCRHKLFSDFFGDPTPDCSGQCDVCKRPKKAEKALEIFHRLCMDDAFKSHI 457
            :..|:.:..|||.|.|||...:.:|||..|.|:..||.||.|...::.:|     .::..|:|..
 Frog   420 MAGFDAMVSFCEDTGCRHAAIAAYFGDEKPQCNKSCDSCKNPLAVKRQVE-----QLEGLFQSGR 479

  Fly   458 SLQDCAD--------------LYEGGRPGIKRAAQEYAGGESGSDDDSGQSHSSMAKRAKKESQD 508
            | :.|.:              ||||||.|       |.......|||.|.:..| |:..|:....
 Frog   480 S-RTCIEKPAGPKGPFGFEPGLYEGGRKG-------YGFARYDDDDDEGGAAES-AEDRKRVWNS 535

  Fly   509 FIKQQFNLRKQISAARQLEQETIAQISRVRMAEATEKKIAGLQATHREKYLTALIDALKANVDKC 573
            |.::|.||||    :::|| :.|.......:.:|:..||..|....||..|..|.:||..|....
 Frog   536 FYQKQMNLRK----SKELE-DFIPPSDDCPLKDASSDKIPKLTVKAREHCLNILEEALAKNARAA 595

  Fly   574 KDEPGQQPKSVLKYNDYEAMSVNMEYDVFRQNKVANMYRHALVKEISTIKKL------------- 625
            ..|         ...|.|:.:|::||:|||.:|:.|:|:.|:||::..|:.|
 Frog   596 AAE---------HRTDVESCAVDLEYEVFRSSKLCNLYKAAIVKKVKEIEALKDGELHSALGSSN 651

  Fly   626 TEQTKLLPLLVDYIPKPETSSKGAWTGGSVAYFERKLKELE----EQRP---------------- 670
            :||....|....::...:..:......|:::.|:.....|.    |:||
 Frog   652 SEQRTETPATDGFMSASQMLTSKCKRVGALSSFQSASDLLRTTQPERRPVESSQGTSQEMAASND 716

  Fly   671 QSLKEVP---KALKDRKGFKQENSKQ----------TSISSFF-----------KKEIKEEPIDS 711
            .|:.:.|   |.....|..:....:|          .:||.||           |.:::.:|.:.
 Frog   717 SSIPDKPDSKKVASPSKAARPSKKRQELANAAKKDSQNISKFFSSHCKAQPQSGKNDVQAKPGNP 781

  Fly   712 PIQEERVNIKSEQMDLE------------------ESTP------KDIASNHVKEES-------- 744
            .::|..::.|.:.:..:                  ||:|      :|..:..:.|.|
 Frog   782 TLKEGSLSQKDDTLTSDGLQGEPPAPVSTELGEGAESSPEEQSLCRDTWAGQIVEPSEYNCRNVP 846

  Fly   745 -VTPESSSSDRELELQP-DSIIGERKFKLMSNGDGS---YDTHRRKRVSHETQPKEKESIKTKSS 804
             |.|..:.|   |.:|| ||..|:   .|..:|..|   :.....|.|..|::|:|.:.:.||:|
 Frog   847 AVEPSDTGS---LYVQPGDSPPGQ---PLQDHGRTSVSLFHPDPLKPVEDESEPEEHQEMSTKTS 905

  Fly   805 MQHLFGSFKSESEESNQSLNGFKTARQMLEENNSKLEGVPEKLPIKDGEKRVLENRADSIGFTSA 869
            .                                   |..|.|...:|.|||..|.: ||.|..
 Frog   906 R-----------------------------------EEAPSKPRTRDREKRPAEGQ-DSEGPV-- 932

  Fly   870 REMLERSKQREGDDKSSNKLEKLGFISAREMLEKNKLNERCLDKKDVKEKKLESRETKRSLQNNE 934
                 |.:.|| :.|||:.|..:..:|..:            .||.|            :...|.
 Frog   933 -----RKRPRE-EIKSSSILAPVHKVSTNQ------------GKKKV------------TFDPNL 967

  Fly   935 LQHKQEEDRKDKASHRKTSKESLSNLKKEGSDSRVLQKDTKPETRNHQKTDVSKNVVQWLNPYYK 999
            ..|               .||..:.:.:..|.::|:   |..||     .||   ||::|.|:::
 Frog   968 CPH---------------DKEGTAKILQPPSGNKVM---TLKET-----ADV---VVKYLTPFFR 1006

  Fly  1000 R-KIATKELFKALAKLLTQRI 1019
            . |.|:|:||||.|:.|:..:
 Frog  1007 EGKFASKDLFKAFARHLSHHL 1027

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RecQ5	NP_729983.1	RecQ	6..>442	CDD:223588	215/438 (49%)
		DEAD	37..193	CDD:278688	87/155 (56%)
		HELICc	<257..359	CDD:238034	60/101 (59%)
		RecQ_Zn_bind	364..431	CDD:292742	22/67 (33%)
recql5	XP_031749855.1	RecQ	35..>462	CDD:223588	214/431 (50%)
		RecQ5	667..811	CDD:399738	19/143 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	192	1.000	Domainoid score	I3163
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	504	1.000	Inparanoid score	I1310
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D251827at33208
OrthoFinder	1	1.000	-	-		FOG0006219
OrthoInspector	1	1.000	-	-		oto103930
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4493
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060