Protein Alignment shd and cyp11a1

DIOPT Version :9

• Sequence 1: NP_001261843.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_694485.2
• Gene: cyp11a1 / 80374
• ZFINID: ZDB-GENE-010306-1
• Length: 509
• Species: Danio rerio
• Alignment Length: 492
• Identity: 124/492 - (25%)
• Similarity: 214/492 - (43%)
• Gaps: 51/492 - (10%)

  Fly    62 IPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYADLNRQYGDIVLEVMPSNVPI---VHLYNRDDL 123
            |||..|...|..    |.|.:...:..:|.:.....:.:|.|..|    .|.|   |::...:|.
Zfish    44 IPGRWRNSLLSV----LAFTKMGGLRNVHRIMVHNFKTFGPIYRE----KVGIYDSVYIIKPEDG 100

  Fly   124 EKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLP 188
            ..:.|....:|.|...:....||..|..:|   |::.::|..|:..|..|...:..|::...|:|
Zfish   101 AILFKAEGHHPNRINVDAWTAYRDYRNQKY---GVLLKEGKAWKTDRMILNKELLLPKLQGTFVP 162

  Fly   189 ALNAVCDDFI-----ELLRARRDPDT--LVVPNFEELANLMGLEAVCTLMLGRRMGFLAIDTKQP 246
            .|..|..||:     ::.|:.:...|  |....|:     ..||:|..::.|.|:|.| :|...|
Zfish   163 LLEEVGQDFVARVNKQIERSGQKQWTTDLTHDLFK-----FSLESVSAVLYGERLGLL-LDNIDP 221

  Fly   247 QKISQLAAAVKQLFISQRDS-YYGLGLWKYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKSA 310
            : .......|..:|.:.... |...||.:...:..:::...|.|.|::.....|.:..::.|
Zfish   222 E-FQHFIDCVSVMFKTTSPMLYLPPGLLRSIGSNIWKNHVEAWDGIFNQADRYIQNIFKQWK--- 282

  Fly   311 ACEDDEAAGLRSIFLNILELKD-LDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPRI 374
              |:.|..|.....|.||.::| |.|.|.|:::.:.:|.|::::..|||:.|..:...|.....:
Zfish   283 --ENPEGNGKYPGVLAILLMQDKLSIEDIKASVTELMAGGVDSVTFTLLWTLYELARQPDLQDEL 345

  Fly   375 LSEFCEYR---DTNILQDALTNATYTKACIQESYRLRPTAFCLARILEEDMELSGYSLNAGTVVL 436
            .:|....|   ..:::| .:......||.::|:.||.|.|..|.|.:.||..:..|.:.|||:|.
Zfish   346 RAEISAARIAFKGDMVQ-MVKMIPLLKAALKETLRLHPVAMSLPRFITEDTVIQNYHIPAGTLVQ 409

  Fly   437 CQNMIACHKDSN-FQGAKQFTPERWIDPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVL 500
            . .:.|..:|.. |...:|:.|.|||....:.|.        .:.||.|.|.|.|:|..|.|:.:
Zfish   410 L-GVYAMGRDHQFFPKPEQYCPSRWISSKRQYFK--------SLGFGFGPRQCLGRRIAETEMQI 465

  Fly   501 LLAKMVLAFDVSFVKPLE--TEFEFLLAPKTPLSLRL 535
            .|..|:..|.:...|.:|  ::||.||.|:.|:.|.:
Zfish   466 FLIHMLENFRIEKQKQIEVRSKFELLLMPEKPIMLTI 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_001261843.1	p450	63..528	CDD:299894	120/482 (25%)
cyp11a1	NP_694485.2	p450	66..502	CDD:278495	117/464 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820