Protein Alignment shd and cyp27a1.3

DIOPT Version :9

• Sequence 1: NP_001261843.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_002934001.3
• Gene: cyp27a1.3 / 594905
• XenbaseID: XB-GENE-18386061
• Length: 518
• Species: Xenopus tropicalis
• Alignment Length: 495
• Identity: 125/495 - (25%)
• Similarity: 226/495 - (45%)
• Gaps: 47/495 - (9%)

  Fly    61 DIPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYADLNRQYGDIVLEVMPSNVPIVHLYNRDDLEK 125
            |:|||..:..|  .||||   |.| :.:.||:.....:.||. :.::......:|.:.:.|.||.
 Frog    49 DLPGPSPLKLL--YWIFL---RGY-LFRTHELQVIFKKTYGP-MWKMSDRQHAMVTVASPDLLES 106

  Fly   126 VLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPAL 190
            :|:...|||.|  .::.:| |:.|..|..|.|.|.|:|..|.|:|:.|...:..||....:..::
 Frog   107 LLRKEGKYPTR--ADMFIM-REHRDLRGHSYGPVTEEGHQWHRIRTILNQRMLKPRETVVYAGSM 168

  Fly   191 NAVCDDF---IELLRARRDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFLAID-TKQPQK-IS 250
            |.|..|.   |:.|.|:....| .|....||......|::||::...|:|.|..: ..:.|| |.
 Frog   169 NEVVSDLLLKIKELTAQSSSGT-QVNGVAELMYKFAFESICTVLFETRLGCLNKEILPETQKFID 232

  Fly   251 QLAAAVKQLFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYDVISEIIDHELEE----LKKSAA 311
            .:...::.|.:..|...:..|:..|     :..:..|.|.|:|...::||.::|:    ||:...
 Frog   233 SIGIMLEHLTMLTRLPQWTKGILPY-----WGRYIEAWDTIFDFGKKLIDKKMEDIEGRLKRGEE 292

  Fly   312 CEDDEAAGLRSIFLN-ILELKDLDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPRIL 375
            .|.:        :|. :|....|.:.:...::::.:.||::|.:|||.:.|..::.:|.....:.
 Frog   293 VEGE--------YLTYLLSSGKLSMEEVYGSVVELLQAGVDTTSNTLTWALYQLSRNPEIQNNLY 349

  Fly   376 SEFCEYRDTNILQD--ALTNATYTKACIQESYRLRPTAFCLARIL-EEDMELSGYSLNAGTVVLC 437
            .|.........:.|  |:......||.|:|:.||.|.....||:: |:::.:..|.....|..:.
 Frog   350 QEVIRVIPGETIPDSEAIARMPLLKAVIKETLRLFPVVPENARMINEKEVTIKDYVFPVKTQFIL 414

  Fly   438 QNMIACHKDSNFQGAKQFTPERWI-DPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLL 501
            .:......::.|..|.:|.||||: |...::....      .:|||.|.|:|.|:|..|:|:.|.
 Frog   415 GHYAISRDETTFPEADRFLPERWLRDSGMKHHPFG------SIPFGYGVRACVGRRIAELEMHLA 473

  Fly   502 LAKMVLAFDV---SFVKPLETEFEFLLAPKTPLSLRLSDR 538
            |::::..|.|   ..:..:..:...:|....|::||..:|
 Frog   474 LSRIIKMFQVIPDPDLGEVGAKNRAVLVANRPVNLRFIER 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_001261843.1	p450	63..528	CDD:299894	120/481 (25%)
cyp27a1.3	XP_002934001.3	cytochrome_P450	79..508	CDD:425388	109/452 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010