Protein Alignment shd and cyp27c1

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001106808.2
• Gene: cyp27c1 / 558396
• ZFINID: ZDB-GENE-080204-68
• Length: 540
• Species: Danio rerio
• Alignment Length: 511
• Identity: 127/511 - (24%)
• Similarity: 237/511 - (46%)
• Gaps: 45/511 - (8%)

  Fly    44 AELIQPEAPKRRRRGIWDIPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYADLNRQYGDIVLEVM 108
            ||.:|..|   |.:.:.::|||..:..|      |.||.|...:::||:..:..::||.|.....
Zfish    58 AEEVQKAA---RVKSLKEMPGPSTVANL------LEFFYRDGFSRIHEIQMEHAKKYGKIFKSRF 113

  Fly   109 PSNVPIVHLYNRDDLEKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSL 173
            .... :|.:.:||.:.:||:..|..|.|...|   .:::.|..|..|.|:::.:|..|.::||.|
Zfish   114 GPQF-VVSIADRDMVAQVLRSESATPQRGNME---SWKEYRDLRGRSTGLISAEGDEWLKMRSVL 174

  Fly   174 TSSITSPRVLQNFLPALNAVCDDF---IELLRARRDPDTLVVPNFEELANLMGLEAVCTLMLGRR 235
            ...|..||.:..|...:|.|..|.   ::.||:::| |:..|.|..:|.....:|.|.|::...|
Zfish   175 RQLIMRPRDVAVFSSDVNDVVADLVKRVKTLRSQQD-DSQTVLNINDLFFKYAMEGVATILYETR 238

  Fly   236 MGFLAIDTKQPQKISQLAAAVKQLFISQRDSYYGLGLWKYFP---TKTYRDFARAEDLIYDVISE 297
            :|  .::.:.|:...:...|:..:|.|.:.:.|...:.|:..   .|.:.:|..:.|.::.....
Zfish   239 LG--CLENEIPKMSQEYITALHLMFSSFKTTMYAGAIPKWLRPIIPKPWEEFCSSWDGLFKFSQI 301

  Fly   298 IIDHELEELKKSAACEDDEAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIETLANTLLFVLS 362
            .:|..|.|:||.....::...||   ..::|..:::::.:..:.:.:.:.||::|.:.||.:...
Zfish   302 HVDKRLSEIKKQMEKSEEIKGGL---LTHMLVTREMNLEEIYANMTEMLLAGVDTTSFTLSWSTY 363

  Fly   363 SVTGDPGAMPRILSEFCEYRDTNI-LQDALTNATYTKACIQESYRLRPTAFCLARILEEDMELSG 426
            .:...|....:|..|........: ..:.:......:..::|:.||.|......|:..:|:.:.|
Zfish   364 LLARHPTIQQQIFEEVDRVLGGRVPTGEDVPYLPLIRGLVKETLRLFPVLPGNGRVTHDDLIVGG 428

  Fly   427 YSLNAGTVVLCQNMIACH-----KDSNFQGAKQFTPERWIDPATENFTVNVDNASIVVPFGVGRR 486
            |.:..||     .:..||     .:.||...::|.|:|||   .::.:..|||.. .:|||.|.|
Zfish   429 YLIPKGT-----QLALCHYSTSMDEENFPRPEEFRPDRWI---RKDASDRVDNFG-SIPFGYGIR 484

  Fly   487 SCPGKRFVEMEVVLLLAKMVLAFDVSFVKPLETEFEF----LLAPKTPLSLRLSDR 538
            ||.|:|..|:|:.|.|.:::..|.:. |.|..||...    ||.|...::||.:||
Zfish   485 SCIGRRIAELEMHLALTQLLQNFHIE-VSPQTTEVHAKTHGLLCPGASINLRFTDR 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	108/449 (24%)
cyp27c1	NP_001106808.2	cytochrome_P450	102..533	CDD:477761	108/450 (24%)