Protein Alignment shd and cyp27a2

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_686522.4
• Gene: cyp27a2 / 558239
• ZFINID: ZDB-GENE-120215-110
• Length: 573
• Species: Danio rerio
• Alignment Length: 491
• Identity: 128/491 - (26%)
• Similarity: 231/491 - (47%)
• Gaps: 37/491 - (7%)

  Fly    61 DIPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYADLNRQYGDIVLEVM-PSNVPIVHLYNRDDLE 124
            |:|||.    |.|. ::.||.:.| ..|.|.:..:..|.||.|..... |.:|  :::...|.:.
Zfish   106 DLPGPN----LATT-VYWLFVKGY-ADKSHAMQVEHKRLYGPIWRSRFGPFDV--INVAGADLIA 162

  Fly   125 KVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPA 189
            :|::...:||.|..   :..:|:.|..|..:.||..:.||.|.|:||:|...:...:.:..:.|.
Zfish   163 QVIRQEGRYPVRTD---LPHWREYRDMRGQAYGIHVDTGPEWYRIRSALNPKMLKLKEVTAYAPI 224

  Fly   190 LNAVCDDF---IELLRARRDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFLAIDTKQPQKISQ 251
            ::.|..|.   :||||. |.||.:.|.:........|.|.:.:::...|:|  .:..:.|....:
Zfish   225 IHEVVSDLLQRLELLRL-RSPDQITVSDLASELYKFGFEGISSILFETRLG--CLQEEIPTDTLR 286

  Fly   252 LAAAVKQ-LFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKSAACEDD 315
            ..:||.: |.:|:...::.......||  .::.|.:|.|.:|||...:||.::.|::...| ..:
Zfish   287 FISAVNEMLALSETVLFFPRWTRHIFP--FWKRFVQAWDELYDVARHLIDKKVNEIRDQVA-RGE 348

  Fly   316 EAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPRILSEF-- 378
            |..|:...:|  |....|.:.:...::.:.:..|::|.:|||.:.|..:..:|....|:.:|.
Zfish   349 EVEGMYLTYL--LSSNKLSLGEVYISLTELLLGGVDTTSNTLSWTLYHLARNPEIQKRLHNEIVS 411

  Fly   379 -CEYRDTNILQDALTNATYTKACIQESYRLRPTAFCLARI-LEEDMELSGYSLNAGTVV-LCQNM 440
             |..:......| ||...|.||.|:|..|:.|......|: ::.|:.:..|.....|.. ||...
Zfish   412 VCPNKKVPNTDD-LTKMPYMKAVIKEILRMYPVVPGNGRLTVDSDIVVDNYWFPKKTQFHLCHYA 475

  Fly   441 IACHKDSNFQGAKQFTPERWIDPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKM 505
            :: |.::||..|::|.|||||..:...   :..:....||||||.|:|.|||..|:|:...|:::
Zfish   476 VS-HDENNFPDAERFVPERWIRDSPSR---SQHHPYSSVPFGVGVRACVGKRVAELEMYFALSRL 536

  Fly   506 VLAFDV---SFVKPLETEFEFLLAPKTPLSLRLSDR 538
            :..::|   :....::.:...||.|..|:.|:...|
Zfish   537 MQQYEVRTKAGSPSIQPKTRTLLIPSQPIDLQFIPR 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	115/446 (26%)
cyp27a2	XP_686522.4	cytochrome_P450	136..567	CDD:477761	115/448 (26%)