Protein Alignment shd and Cyp2j7

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001411962.1
• Gene: Cyp2j7 / 546837
• MGIID: 2449816
• Length: 504
• Species: Mus musculus
• Alignment Length: 563
• Identity: 123/563 - (21%)
• Similarity: 222/563 - (39%)
• Gaps: 117/563 - (20%)

  Fly    10 ALVLGCYCALHRHKLADIYLRPLLKNTLLEDFYHAELIQPEAPKRRRRGIWDIPGPKRIPFLGTK 74
            :||...:.|:|...|    |..||...||.|:.          |.||...:. |||.|:||:|..
Mouse     7 SLVARIWSAIHLWTL----LLTLLVFRLLADYL----------KNRRPKNYP-PGPWRLPFVGNL 56

  Fly    75 WIFLLFFRRYKMTKLHEVYADLNRQYGDI-------VLEVMPSNVPIVHLYNRDDLEKVLKYPSK 132
            :.|.|     .:::||.......::||::       :..|:.:.:|::.....|..:.:||.|
Mouse    57 FQFDL-----DVSQLHLRIQLFVKKYGNLISIDFGNISSVVITGLPLIKEAFTDMEQNLLKRP-- 114

  Fly   133 YPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAVCDDF 197
                    ||    .||...:...||:...|..|:..|......:.|..:.:..|.  ..:.::.
Mouse   115 --------II----PSRKHVFKDNGIIFSSGQKWKEQRRFALMILKSFGLGKKSLE--QRIQEEA 165

  Fly   198 IELLRARRDP-----DTLVVPNF---EELANLMGLEAVCTLMLGRRMGFLAIDTKQPQKISQ--L 252
            ..|::|..:.     |    |:|   ..::|:     :|::..|.|..:.....::..||:.  |
Mouse   166 YHLVKAMEEEKGQPFD----PHFRINSAVSNI-----ICSINFGERFEYGDNKFQELLKITNETL 221

  Fly   253 AAAVKQLFISQRDSYYGL-GLWKYFP---TKTYRDFARAEDLIYDVISEIIDHELEELKKSAACE 313
            :|....:.:    .|..| .:.||.|   ...:|::.|.:.::|        |.:|..:|.  ..
Mouse   222 SAETSMMLV----LYNALPSIMKYLPGPHQTVFRNWERLKMIVY--------HMMESHRKD--WN 272

  Fly   314 DDEAAGLRSIFLNILELKDLDIRDKKS--------AIIDFIAAGIETLANTLLFVLSSVTGDPGA 370
            .||.......||.  |:.....:...|        :.:|...||.||.:..|.:.|..:|.:|..
Mouse   273 PDEPRDFIDAFLT--EMTKYPDKTTTSFNEENLICSCLDLFIAGTETSSTALRWALLYMTLNPEV 335

  Fly   371 MPRILSE----FCEYRDTNI-LQDALTNATYTKACIQESYRL-RPTAFCLARILEEDMELSGYSL 429
            ..|:.||    ..::|..:. .:|::   .||.|.|.|..|: ......:.|.:..|..|:|:.|
Mouse   336 QERVHSEIDGVIGQWRQPSTGDRDSM---PYTNAVIHEVLRMGNIVPLNVPREVTADSTLAGFHL 397

  Fly   430 NAGTVVLCQNMIACHKDSNFQGAKQFTPERWIDPATENFTVNVDNASI-----VVPFGVGRRSCP 489
            ..|.::| .|:.|.|:|          |:.|..|...|....::|...     .:||.:|:|:||
Mouse   398 PKGKMIL-TNLTALHRD----------PKEWATPDIFNPEHFLENGQFKKRESFLPFSMGKRACP 451

  Fly   490 GKRFVEMEVVLLLAKMVLAFDVSFVKPLETEFEFLLAPKTPLS 532
            |::....|:.:....::..|  :|..|:..:.........|:|
Mouse   452 GEQLARTELFIFFTALMQKF--TFKAPVNEKLSLKFRMSVPIS 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	97/473 (21%)
Cyp2j7	NP_001411962.1	None