Protein Alignment shd and cyp27b1

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001006907.1
• Gene: cyp27b1 / 448754
• XenbaseID: XB-GENE-942527
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 550
• Identity: 131/550 - (23%)
• Similarity: 245/550 - (44%)
• Gaps: 97/550 - (17%)

  Fly    24 LADIYLRPLLKNTLLEDFYHAELIQPEAPKRRRRGIWDIPGPKRIPFLGTKWIFLLFFRRYKMTK 88
            |.:::...:|||:             |...:..:.:.|:|||..:.|:..     ||.|| .:.:
 Frog    19 LQELWAETVLKNS-------------EKVIKGHKSLADMPGPSTVSFISD-----LFCRR-GLAR 64

  Fly    89 LHEVYADLNRQYGDIVLEVMPSNVPI--VHLYNRDDLEKVLKYPSKYPFRPPTEIIVMYRQSRPD 151
            |||:..:...::|.:   ...|..||  ||:.....:|:||:...|:|.|........|||.|..
 Frog    65 LHELQLEGKAKFGPV---WKASFGPILTVHVAEPSLIEQVLRQEGKHPIRSDLSSWKDYRQCRGH 126

  Fly   152 RYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDPD-TLVVPNF 215
            .|   |::..:|..||:.||.|...:..|:.::.:...||.|..|.|:.:..:|..: ..||.:.
 Frog   127 SY---GLLTAEGEEWQQFRSILGKHMLKPKEVEAYSDVLNDVVGDLIKKINYQRSQNQNNVVKDI 188

  Fly   216 EELANLMGLEAVCTLMLGRRMGFLAIDTKQPQKISQLAAAVKQLFISQRDSYYGLGLWKYFP--- 277
            .:...:.|||.:.:::...|:|  .::...|::..:...::..:|:.   :...:.:.|:..
 Frog   189 AKEFYMFGLEGISSVLFESRIG--CLEPTVPKETEKFIQSINTMFVM---TLLTMAMPKFLHKIF 248

  Fly   278 TKTYRDFARAEDLIYDVISEIIDHELEELKKSAACEDDEAAG-------------LRSIFLNILE 329
            .|.::.|..:.|.::......||..::::.:..| :.::..|             ::||:.|:.|
 Frog   249 RKPWQKFCESWDYMFAFAKGHIDKRMKDVAQKLA-QGEKVEGKYLTYYLAQEKIPMKSIYGNVTE 312

  Fly   330 LKDLDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPRILSEFCEYRDTNILQ------ 388
            |               :.||::|:::||.:.|..:...|.....:.||..|     |||
 Frog   313 L---------------LLAGVDTISSTLSWSLYELAQHPDIQSAVYSEVEE-----ILQGKQIPS 357

  Fly   389 -DALTNATYTKACIQESYRLRPTAFCLARIL-EEDMELSGYSLNAGTVV-LCQNMIACHKDSN-F 449
             ..:......||.::|..||.|.....||:: :.|:::..|.:...|:: ||.  .|..:|.| |
 Frog   358 PSDVARMPLLKAVVKEVLRLYPVIPGNARVVADRDIQVGDYIIPKKTLITLCH--YATSRDENVF 420

  Fly   450 QGAKQFTPERWIDPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDV--- 511
            ....:|.|:||:.....:...    ||:  |||.|:|||.|:|..|:||.|.||:::..|:|
 Frog   421 SNPNEFQPDRWLKKEDTHHPY----ASL--PFGFGKRSCIGRRIAELEVYLALARILSHFEVKPE 479

  Fly   512 ---SFVKPLETEFEFLLAPKTPLSLRLSDR 538
               |.|.|:.   ..||.|:..::|:..:|
 Frog   480 QPGSLVMPMT---RTLLVPEKEINLQFLER 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	112/468 (24%)
cyp27b1	NP_001006907.1	CYP27B1	72..501	CDD:410741	112/471 (24%)