Protein Alignment shd and Cyp12a4

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 140/478 - (29%)
• Similarity: 227/478 - (47%)
• Gaps: 35/478 - (7%)

  Fly    83 RYKMTKLHEVYADLNRQYGDIVLEVMP---SNVPIVHLYNRDDLEKVLKYPSKYPFRPPTEIIVM 144
            :||..:|.|::..:.:.||||..  ||   .|.|.:..:|..|.|.|.:....:|.||....::.
  Fly    68 KYKNMELMEMFEAMRQDYGDIFF--MPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLY 130

  Fly   145 YRQS-RPDRYASV-GIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDP 207
            :|:. |.|.|..| |::..||..|...|:.:...:..|:.::.:...::.|..:|::.:...|||
  Fly   131 HREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDP 195

  Fly   208 DTLVVP-NFEELANLMGLEAVCTLMLGRRMGFLAIDTKQPQKISQLAAAVKQLFISQRDSYYGLG 271
            |||..| :|.:..|...||:|..:.|.:::|.|....|:.:.: :|...:.:.||...|......
  Fly   196 DTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNKESEAL-KLFHYLDEFFIVSIDLEMKPS 259

  Fly   272 LWKYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKSAACEDDEAAGLRSIFLNILELKDLDIR 336
            .|:|..|...:...||.|.|.:|....:|..:|.|.|.|..........:|:...:|::
  Fly   260 PWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRPENEQSVLEKLLKV------ 318

  Fly   337 DKKSAII---DFIAAGIETLANTLLFVLSSVTGDPGAMPRILSEFCEY---RDTNILQDALTNAT 395
            |:|.|.:   |.:.||::|.::|...:|..:..:|....|:..|..:.   :::...:.::.|..
  Fly   319 DRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVP 383

  Fly   396 YTKACIQESYRLRPTAFCLARILEEDMELSGYSLNAGTVVLCQNMIACHKDSNFQGAKQFTPERW 460
            |.:|||:||.||.|.....||:|..|..||||.:.|||.|....:.|..:|..|..|.:|.||||
  Fly   384 YLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPERW 448

  Fly   461 ID---------PATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFVKP 516
            :.         ||.|   :...|..:.:|||.|.|.|.|||.||||:.|..|:::..|:|.|..|
  Fly   449 LRSPKDSESKCPANE---LKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNYP 510

  Fly   517 LETEFEFLL--APKTPLSLRLSD 537
            .|..|...|  .|..||..:..|
  Fly   511 TENAFRSALINLPNIPLKFKFID 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	134/456 (29%)
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	134/457 (29%)