Protein Alignment shd and Cyp12a5

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 473
• Identity: 134/473 - (28%)
• Similarity: 232/473 - (49%)
• Gaps: 25/473 - (5%)

  Fly    83 RYKMTKLHEVYADLNRQYGDIV-LEVMPSNVPIVHLYNRDDLEKVLKYPSKYPFRPPTEIIVMYR 146
            :||..::.|:...|.:.||:|: |..|.....:|..:|..|.|.|.:....:||||.::|:..:|
  Fly    68 KYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHR 132

  Fly   147 Q-SRPDRYASV-GIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDPDT 209
            . .|.|.:..| ||:..||..|...||.:...:..|:.::.:...::.|..:|:||::..||..|
  Fly   133 TVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKEIRDAST 197

  Fly   210 LVVP-NFEELANLMGLEAVCTLMLGRRMGFLAIDTKQPQKISQLAAAVKQLFISQRDSYYGLGLW 273
            ..|| ||.|..|...||:|..:.|.:::|.|. ::.:..:.::|...:.:.|:...|......||
  Fly   198 QEVPGNFLETINRWTLESVSVVALDKQLGLLR-ESGKNSEATKLFKYLDEFFLHSADLEMKPSLW 261

  Fly   274 KYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKSAACEDDEAAGLRSIFLNILELKDLDIRDK 338
            :||.|...:...|..|.:.:|..:.:|..:|.|:|.|..........:|:...:|::      ||
  Fly   262 RYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHEQSVLEKLLKV------DK 320

  Fly   339 KSAII---DFIAAGIETLANTLLFVLSSVTGDPGAMPRILSEFCEY---RDTNILQDALTNATYT 397
            |.|.:   |.:.||::|.::|...:|..:..:|....|:..|..:.   :|:...:.::.|..|.
  Fly   321 KVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEASMKNVPYL 385

  Fly   398 KACIQESYRLRPTAFCLARILEEDMELSGYSLNAGTVVLCQNMIACHKDSNFQGAKQFTPERWID 462
            :|||:||.|:.|.....||.|..|..:|||.:.|||:|....:.:.:.:..|....:|.||||:.
  Fly   386 RACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEEYFPKPTEFLPERWLR 450

  Fly   463 PATENF------TVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFVKPLETEF 521
            .|:::.      .:...|..:.:|||.|.|.|.|||.||||:.|..|:::..|:|.|....:..|
  Fly   451 NASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAF 515

  Fly   522 EFLL--APKTPLSLRLSD 537
            ...|  .|..||..:.:|
  Fly   516 RSALINLPNIPLKFKFTD 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	128/451 (28%)
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	128/452 (28%)