DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shd and Cyp313b1

DIOPT Version :9

Sequence 1:	NP_001261843.1	Gene:	shd / 39592	FlyBaseID:	FBgn0003388	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	538	Identity:	122/538 - (22%)
Similarity:	211/538 - (39%)	Gaps:	120/538 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 RRR--RGIWDIPGPKRIPFLG------TKWIFLLFFRRYKMTKLHEVYAD-LNRQYGDIVLEVMP 109
            |||  :..|.:.||...|.:|      ....||             .|.| |:||:....:..|.
  Fly    22 RRRYYKVAWQLRGPIGWPLIGMGLQMMNPETFL-------------QYMDGLSRQFKAPFISWMG 73

  Fly   110 SNVPIVHLYNRD--DLEKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASV------GIVNEQGPMW 166
            ::   ..||..|  .:|::|.              ..:..::.|.|..:      |:.....|.|
  Fly    74 TS---CFLYINDPHSVEQILN--------------STHCTNKGDFYRFMSSAIGDGLFTSSSPRW 121

  Fly   167 QRLRSSLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDPDTLVVPNFEELANLMGLEAVCTLM 231
            .:.| .|.:.....::|.||||..||..:..::.|..........:..::.|..:: |||.|...
  Fly   122 HKHR-RLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIV-LEAACQTT 184

  Fly   232 LGRRMGF-----LAIDTKQPQKISQLAAAVKQLFISQRDSYYGLGLWKYFPTKTYR--DFARAED 289
            :|::|.|     |.| .|....::::  .||::          |..|.| |...||  ...|.:.
  Fly   185 MGKKMNFQHDGSLCI-FKAYNGLTEV--CVKRM----------LSPWLY-PDLIYRRSGLFRLQQ 235

  Fly   290 LIYDVISEIIDHELEELKKSAACEDD--------EAAG-LRSIFLNIL-------ELKDLDIRDK 338
            .:..::...|:..||.:....|...:        |..| .::||:..:       :|...|:||:
  Fly   236 KVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDVRDE 300

  Fly   339 KSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPR----ILSEFCEYRDTNILQDALTNATYTKA 399
            .:..   |||..||.:..|.|.:..:...|....:    :::|.....|.|:.|  |....||:.
  Fly   301 ANVT---IAATFETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGDINLEQ--LQRLEYTEM 360

  Fly   400 CIQESYRLRPTAFCLARILEEDMEL----SGYSLNAGTVVLCQ--NMIACHKDSNFQG--AKQFT 456
            .|.|:.||......:.|..::|::|    ..:.:..||.:...  ||   .:|....|  ::.:.
  Fly   361 VINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNM---QRDERVWGPLSRTYN 422

  Fly   457 PERWIDPATENFTVNVD--NASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFVKPLET 519
            |:       .:|.::..  :|...|||..|.|.|.|.|:.:|.:.||||::..::.:|    .|.
  Fly   423 PD-------AHFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRIS----TEA 476

  Fly   520 EFEFLLAPKTPLSLRLSD 537
            ..|.||. |..:||:|.|
  Fly   477 RLEELLV-KGNISLKLKD 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_001261843.1	p450	63..528	CDD:299894	113/516 (22%)
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	109/505 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100