Protein Alignment shd and Cyp12b2

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 135/509 - (26%)
• Similarity: 232/509 - (45%)
• Gaps: 55/509 - (10%)

  Fly    54 RRRRGIWDIPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYADLNRQYGDI-VLEVMPSNVPIVHL 117
            ::.|...:||||..:..|.    |.:.....:.|.|.::...:...|||| .:..|......|..
  Fly    48 QQARSFGEIPGPSLLRMLS----FFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFT 108

  Fly   118 YNRDDLEKVLKYPSKYPFRPPTEIIVMYRQ-SRPDRYASV-GIVNEQGPMWQRLRSSLTSSITSP 180
            ||.||.|...:....:|.|...|.:..||: .|||.:..| |:.::||..|..:|:.:...:...
  Fly   109 YNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKV 173

  Fly   181 RVLQNFLPALNAVCDDFIELLRARRDPDT-LVVPNFEELANLMGLEAVCTLMLGRRMGFLAIDTK 244
            :.::..||.|:.:..:||:.|..:|:|:| .:..:|.....:...|::..:.|..|||.|: |..
  Fly   174 QNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTRMGLLS-DNP 237

  Fly   245 QPQKISQLAAAVKQLFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKS 309
            .| ...:||..::..|...........:|.::.|..::.|.:..|.|.|:.|..|:..:....|:
  Fly   238 DP-NADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIETAMRGFGKN 301

  Fly   310 AACEDDEAAGLRSIFLNILELKDLDIRDKKSA---IIDFIAAGIETLANTLLFVLSSVTGDPGAM 371
                ||  ...:.:...:||      .:||.|   ::|.:.|||:|.::..|.:|..:..:|...
  Fly   302 ----DD--GKTKCVLEQLLE------HNKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQ 354

  Fly   372 PRILSEFCEYRDTNILQDALT-----NATYTKACIQESYR---LRPTAFCLARILEEDMELSGYS 428
            .::..|......|.  :|:||     |..|.:|||:|..|   :.|..|   ||..:|:.||||.
  Fly   355 EKLRRELLRILPTT--KDSLTDQNTKNMPYLRACIKEGLRITSITPGNF---RITPKDLVLSGYQ 414

  Fly   429 LNAGTVVLCQNMIACHKDSNFQGAKQFTPERWID----------PATENFTVNVDNASIVVPFGV 483
            :..||.||...:...:.|..|..:.:|.||||:.          ||     ....|..:.:|||.
  Fly   415 VPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPA-----ARTRNPFVYLPFGF 474

  Fly   484 GRRSCPGKRFVEMEVVLLLAKMVLAFDVSFV--KPLETEFEFLLAPKTPLSLRL 535
            |.|:|.|||..|:|:..||.:::.::.||::  .|:|.|...:|:|...:..:|
  Fly   475 GPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCGDIRFKL 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	125/460 (27%)
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	125/461 (27%)