Protein Alignment shd and Cyp11a1

DIOPT Version :9

• Sequence 1: NP_001261843.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_058982.1
• Gene: Cyp11a1 / 29680
• RGDID: 69325
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 128/547 - (23%)
• Similarity: 232/547 - (42%)
• Gaps: 68/547 - (12%)

  Fly     5 LLLALALVLGCYCALHRHKLADIYLRPLLKNTLLEDFYHAELIQPEAPKRRRRGIWDIPGPKRIP 69
            |.|...||..|          ..:|.|:.:...|.....|.:....:|    |...:||.|.
  Rat     6 LCLRSVLVKSC----------QPFLSPVWQGPGLATGNGAGISSTNSP----RSFNEIPSPG--- 53

  Fly    70 FLGTKWIFLLFFRRYKMT-KLHEVYADLNRQYGDIVLEVMPSNVPIVHLYNRDDLEKVLKYPSKY 133
              ...||.|..|.|...| ::|..:....::||.|..|.: .|:..|::.:..|...:.......
  Rat    54 --DNGWINLYHFLRENGTHRIHYHHMQNFQKYGPIYREKL-GNMESVYILDPKDAATLFSCEGPN 115

  Fly   134 PFR---PPTEIIVMYRQ--SRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAV 193
            |.|   ||.   |.|.|  .||     :|::.:....|::.|..|...:.:|..::||:|.|..|
  Rat   116 PERYLVPPW---VAYHQYYQRP-----IGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGV 172

  Fly   194 CDDFIELL--RARRDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFL--AIDTKQPQKISQLAA 254
            ..|||::|  |.::........:..:.......|::.:::.|.|:|.|  .:|.:..:.|.
  Rat   173 AQDFIKVLHRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFID---- 233

  Fly   255 AVKQLFISQRDSYYGLG----LWKYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKSAACEDD 315
            ||.|:|   ..|...|.    |::.|.|||::|.|.|.|:|:....|...:...:|::..
  Rat   234 AVYQMF---HTSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKR----- 290

  Fly   316 EAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPRILSEFCE 380
            :.:....:..::|....|..::.::.|.:.:|.|::|.:.||.:.|..:..:......:.:|...
  Rat   291 DFSKYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLA 355

  Fly   381 YR--DTNILQDALTNATYTKACIQESYRLRPTAFCLARILEEDMELSGYSLNAGTVVLCQNMIAC 443
            .|  ....:...:......||.|:|:.||.|.:..|.|.:..|:.|..|.:.|.|:|...:....
  Rat   356 ARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMG 420

  Fly   444 HKDSNFQGAKQFTPERWIDPA--TENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMV 506
            .:.|.|....:|.|.||::.:  |.:|.        .:.||.|.|.|.|:|..|:|:.:.|..::
  Rat   421 RESSFFPNPNKFDPTRWLEKSQNTTHFR--------YLGFGWGVRQCLGRRIAELEMTIFLINVL 477

  Fly   507 LAF--DVSFVKPLETEFEFLLAPKTPL 531
            ..|  :|..::.:.|:|..:|.|:.|:
  Rat   478 ENFRIEVQSIRDVGTKFNLILMPEKPI 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_001261843.1	p450	63..528	CDD:299894	114/484 (24%)
Cyp11a1	NP_058982.1	cytochrome_P450	80..505	CDD:425388	107/454 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820