Protein Alignment shd and Cyp12d1-d

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 134/506 - (26%)
• Similarity: 232/506 - (45%)
• Gaps: 60/506 - (11%)

  Fly    61 DIPGPKRIPFLGTKWIFLLFFRRYKMTKLHEVYADLNRQYGDIVLEVMP---SNVPIVHLYNRDD 122
            :||.|.:..|:..    .:....::...:.|..:.:.::||||.  |||   .....|..:|..|
  Fly    44 EIPRPNKFKFMRA----FMPGGEFQNASITEYTSAMRKRYGDIY--VMPGMFGRKDWVTTFNTKD 102

  Fly   123 LEKVLKYPSKYPFRPPTEIIVMYRQS-RPDRYASV-GIVNEQGPMWQRLRSSLTSSITSPRVLQN 185
            :|.|.:....:|.|...:.||.:|:. |||.|..| |:|..|...|.:|||::......||.|:.
  Fly   103 IEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRM 167

  Fly   186 FLPALNAVCDDFIELLRARRDPDTLVVPN--FEELANLMGLEAVCTLMLGRRMGFLAIDTKQPQK 248
            :...|:.:.::|||.::..|||.||.||.  .:|::.|: .|::..:...|:||.:..:......
  Fly   168 YYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLV-FESLGLVAFDRQMGLIRKNRDNSDA 231

  Fly   249 ISQLAAAVKQLFISQRDSY---YGL----GLWKYFPTKTYRDFARAEDLIYDVISEIIDHELEEL 306
            ::        ||.:.||.:   :.|    .:||...|.|||...|..:...:|..:::....:.|
  Fly   232 LT--------LFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDAL 288

  Fly   307 KKSAACEDDEAAGLRSIFLNILELKDLDIRDKKSAII---DFIAAGIETLANTLLFVLSSVTGDP 368
            :|..  :..|.....|:...::|:      |.|.|:|   |.:.||::..|..|..||..::..|
  Fly   289 EKRR--QAGEKINSNSMLERLMEI------DPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHP 345

  Fly   369 GAMPRILSEFCEY---RDTNILQDALTNATYTKACIQESYRLRPTAFCLARILEEDMELSGYSLN 430
            ....::..|....   :|:.:.::.:.:..|.:|.|:|:.|..|..|...|..:.|:.||||.:.
  Fly   346 DKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVP 410

  Fly   431 AGTVVLCQNMIACHKDSNFQGAKQFTPERWI-DPAT------ENFTVNVDNASIVVPFGVGRRSC 488
            .||.||..:.:...:.:.:....:|.||||: ||.|      ..||        .:|||.|.|.|
  Fly   411 KGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFT--------FLPFGFGPRMC 467

  Fly   489 PGKRFVEMEVVLLLAKMVLAFDVSFVKPLETEFE--FLLAPKTPLSLRLSD 537
            .|||.|::|:...:||::..|.|.|.:.....|:  ||:.|......:.:|
  Fly   468 IGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTD 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	128/462 (28%)
Cyp12d1-d	NP_995812.1	CYP24A1-like	76..515	CDD:410677	128/465 (28%)