Protein Alignment shd and Cyp11b2

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_036670.2
• Gene: Cyp11b2 / 24294
• RGDID: 2454
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 507
• Identity: 123/507 - (24%)
• Similarity: 212/507 - (41%)
• Gaps: 90/507 - (17%)

  Fly    65 PKRI-PFLG------TKWIFLLFFRRYK-----MTKLHEVYADLNRQYGDIVLEVMPSNVPIVHL 117
            ||.: ||..      .||:.::...|.:     ..::|:.:.:|..     :.........||.:
  Rat    34 PKTLKPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQAFQELGP-----IFRHSAGGAQIVSV 93

  Fly   118 YNRDDLEKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRV 182
            ...:|.||:.:..|..|.|...|..|.:|:.|..|.   |:....|..|:..|..|..::.||:.
  Rat    94 MLPEDAEKLHQVESILPRRMHLEPWVAHRELRGLRR---GVFLLNGADWRFNRLKLNPNVLSPKA 155

  Fly   183 LQNFLPALNAVCDDFIELLRAR-----RDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFLAID 242
            :|||:|.::.|..||:|.|:.:     |...|:.|.  :.|.|.. :||....:.|.|:|.|..|
  Rat   156 VQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDVQ--QSLFNYT-IEASNFALFGERLGLLGHD 217

  Fly   243 TKQPQKI-------SQLAAAVKQLFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYDVISEIID 300
            . .|..:       |...:..:.||:.:       .|.::..|:.:::...|    :|||||..:
  Rat   218 L-NPGSLKFIHALHSMFKSTTQLLFLPR-------SLTRWTSTRVWKEHFDA----WDVISEYAN 270

  Fly   301 ------HELEELKKS-------AACEDDEAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIET 352
                  |:...|..|       ||.....|..|.:|..|.:||               .|..::|
  Rat   271 RCIWKVHQELRLGSSQTYSGIVAALITQGALPLDAIKANSMEL---------------TAGSVDT 320

  Fly   353 LANTLLFVLSSVTGDPGAMPRILSEFCEYRDTNIL---QDALTNATYTKACIQESYRLRPTAFCL 414
            .|..|:..|..:..:|.....:..|... .:.:|.   |.|:::....:|.::|:.||.|....|
  Rat   321 TAIPLVMTLFELARNPDVQQALRQETLA-AEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFL 384

  Fly   415 ARILEEDMELSGYSLNAGTVVLCQNMIACHKDSNFQGAKQFTPERWIDPATENFTVNVDNASIVV 479
            .|||..|:.|..|.:.|||:||..........:.|...:::.|:||:: ...:|.        .:
  Rat   385 ERILNSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRPERYMPQRWLE-RKRSFQ--------HL 440

  Fly   480 PFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFVK--PLETEFEFLLAPKT 529
            .||.|.|.|.|:|..|:|::|||..|:..|.|..::  .::..:.|:|.|.:
  Rat   441 AFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDVQMAYRFVLMPSS 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	114/462 (25%)
Cyp11b2	NP_036670.2	cytochrome_P450	74..498	CDD:477761	115/467 (25%)