Protein Alignment shd and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 115/531 - (21%)
• Similarity: 204/531 - (38%)
• Gaps: 114/531 - (21%)

  Fly    55 RRRGIWDIPGPKRIPFLGTKWIFLLFF--------RRYKMTKLHEVYADLNRQYGDIVLEVMPSN 111
            :|||   |.||..:||:|:      |:        |.:.:.|..:::..:...|..:
 Worm    26 KRRG---IEGPVGLPFIGS------FYDLADREKPRGFIINKWTKMFGKVFGYYEGV-------- 73

  Fly   112 VPIVHLYNRDDLEK--VLKYPSKYPFRPPTEII---VMYRQSRPDRYASVGIVNEQGPMWQRLRS 171
            :|::.:.:.|.|::  :.|:...|. |..|.:|   :...|..|    .|.:...:|..|:|||
 Worm    74 IPVLVVSDLDMLQEMFIKKFDCFYA-RKTTNLIHGNLECSQEEP----RVNLFAARGARWKRLR- 132

  Fly   172 SLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDPDTLVVPNFEELANLMGLEAVCTLMLGRRM 236
            :|.|...|.:.|:.....:.......::.:..:.:.:..   |..|.......:.:..|.:|:
 Worm   133 ALASPAFSVKALKQIHETMEDSVFSMVDHMSKQVNGEAF---NIHEYYQEFTYDVISRLAMGQ-- 192

  Fly   237 GFLAIDTKQPQKISQLAAAVKQLFISQRDSYYGLGLWKYFP--------TKTYRDFARAEDL--- 290
                  |...|..::....||::|: :::..|...|...||        |....:..|..|:
 Worm   193 ------TYSEQFNNEGVDIVKKIFL-RKNRVYPWYLAVMFPGFENTIKNTFFNHEAVRGGDVGKL 250

  Fly   291 -------IYDVISEIIDHELEELKK-------------SAACEDDEAAGLRSIFLNILELKDLDI 335
                   ::|.:.|..|:..:.::.             :....:|.|.|::      :| |.:..
 Worm   251 LKFCETAVHDRLKERADNVEQGIENPHNDFIDMFLDYYTDTNIEDNAFGIK------VE-KKVTS 308

  Fly   336 RDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPRILSE---FCEYRDTNILQDALTNATYT 397
            .|...|...|:.||.:|.||||.:....:...|..|.::..|   .|  ...:|..|.:....|.
 Worm   309 EDVIGACFVFLLAGFDTTANTLAYASYLLAKHPQEMRKVQDEIDRIC--TSEHISYDDIGKLRYM 371

  Fly   398 KACIQESYRLRPTA-FCLARILEEDMELSGYSLNAGTVVLCQNMIACHKDSNFQG--AKQFTPER 459
            .|.|:|:.|:.|.| |..:|...:...|..|.:..| |.:..::.|.|......|  |.:|.|||
 Worm   372 DAVIREALRMYPVAWFACSRECVQATTLGNYYIEKG-VRIEADVRALHYSEEIWGKNANEFVPER 435

  Fly   460 WIDPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFVKPLETEFEFL 524
            |::.:..:      |.| .:|||.|.|.|.|.|....|....||.::..|.:            |
 Worm   436 WLESSPRH------NMS-WIPFGAGPRQCVGMRLGLSEAKTALAHLLRRFSI------------L 481

  Fly   525 LAPKTPLSLRL 535
            ..|||...|.|
 Worm   482 AGPKTEKELHL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	101/475 (21%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	103/486 (21%)