Protein Alignment shd and cyp-44A1

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_495052.1
• Gene: cyp-44A1 / 173936
• WormBaseID: WBGene00000375
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 136/511 - (26%)
• Similarity: 248/511 - (48%)
• Gaps: 47/511 - (9%)

  Fly    29 LRPLLKNTLLEDFYHAELIQPEAPKRRRRGIWDIPGPKRIPFLGTKWIFLLFFRRYKMT------ 87
            :|.|.:|  :|...::....|..|.|.   ..:||||:.||.:|....|....:....|
 Worm     5 IRNLAEN--VEKCPYSPTSSPNTPPRT---FSEIPGPREIPVIGNIGYFKYAVKSDAKTIENYNQ 64

  Fly    88 KLHEVYADLNRQYGDIVLEVMP-SNVPIVHLYNRDDLEKVLKYPSKYPFRPP-TEIIVMYRQSRP 150
            .|.|:|    ::||.||.|.:. ....:||:::..|::.||....|.||..| .|....||:.:.
 Worm    65 HLEEMY----KKYGKIVKENLGFGRKYVVHIFDPADVQTVLAADGKTPFIVPLQETTQKYREMKG 125

  Fly   151 DRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDPDTLVVPNF 215
               .:.|:.|..||.|.|||||:..::..|:.:|.:||....|.:|.:..:..::....||  :.
 Worm   126 ---MNPGLGNLNGPEWYRLRSSVQHAMMRPQSVQTYLPFSQIVSNDLVCHVADQQKRFGLV--DM 185

  Fly   216 EELANLMGLEAVCTLMLGRRMGFLAIDTKQPQKISQLAAAVKQLFISQRDSYYGLGLWKYFPTKT 280
            :::|....||:...::..:.:|.|...::....:.:|...:.||....|   .||.:::.|.|.:
 Worm   186 QKVAGRWSLESAGQILFEKSLGSLGNRSEWADGLIELNKKIFQLSAKMR---LGLPIFRLFSTPS 247

  Fly   281 YRDFARAEDLIYDVISEIIDHELEELKKSAACEDDEAAGLRSIFLN-ILELKDLDIRDKKSAIID 344
            :|.....||..|..:..::|..|::||    ..|.::..:|  |.: ::..|:|:.||.|..::.
 Worm   248 WRKMVDLEDQFYSEVDRLMDDALDKLK----VNDSDSKDMR--FASYLINRKELNRRDVKVILLS 306

  Fly   345 FIAAGIETLANTLLFVLSSVTGDPGAMPRILSEFCEYRDTNILQDALTNATYTKACIQESYRLRP 409
            ..:.|:.|.|..|::.|.::...|.|:..|..|..|       ..|.:..|:.:|||:|::|:.|
 Worm   307 MFSDGLSTTAPMLIYNLYNLATHPEALKEIQKEIKE-------DPASSKLTFLRACIKETFRMFP 364

  Fly   410 TAFCLARILEEDMELSGYSLNAGTVV-LCQNMIACHKDSNFQGAKQFTPERWIDPATENFTVNVD 473
            ....::|:.::::.||||.:.|||.| :..|::..|:.......::|.|:||::.:.|      .
 Worm   365 IGTEVSRVTQKNLILSGYEVPAGTAVDINTNVLMRHEVLFSDSPREFKPQRWLEKSKE------V 423

  Fly   474 NASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSF-VKPLETEFEFLLAPK 528
            :....:|||.|.|.|.|:||.|.:::..|||:...:|:.. ..|:...:|.||.|:
 Worm   424 HPFAYLPFGFGPRMCAGRRFAEQDLLTSLAKLCGNYDIRHRGDPITQIYETLLLPR 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	117/436 (27%)
cyp-44A1	NP_495052.1	CYP24A1-like	70..478	CDD:410677	117/438 (27%)