Protein Alignment shd and Cyp11b2

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_034121.4
• Gene: Cyp11b2 / 13072
• MGIID: 88584
• Length: 500
• Species: Mus musculus
• Alignment Length: 490
• Identity: 117/490 - (23%)
• Similarity: 211/490 - (43%)
• Gaps: 56/490 - (11%)

  Fly    65 PKRI-PFLG------TKWIFLL-FFRRYKMTKLHEVYADLNRQYGDIVLEVMPSNVPIVHLYNRD 121
            ||.: ||..      .||:.:: ..|......||.....:.|:.|.|....: ....||.:...:
Mouse    32 PKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHSV-GKTQIVSVMLPE 95

  Fly   122 DLEKVLKYPSKYPFRPPTEIIVMYRQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNF 186
            |.||:.:..|..|.|...|..|.:|:.|..|.   |:....||.|:..|..|..::.||:.:|.|
Mouse    96 DAEKLHQVESMLPRRMHLEPWVAHRELRGLRR---GVFLLNGPEWRLNRLRLNRNVLSPKAVQKF 157

  Fly   187 LPALNAVCDDFIELLRAR-----RDPDTLVVPNFEELANLMGLEAVCTLMLGRRMGFLAIDTKQP 246
            :|.::.|..||:|.|:.:     |...|:.|.  :.|.|.. :||....:.|.|:|.|..|. .|
Mouse   158 VPMVDMVARDFLETLKEKVLQNARGSLTMDVQ--QSLFNYT-IEASNFALFGERLGLLGHDL-SP 218

  Fly   247 QKI-------SQLAAAVKQLFISQRDSYYGLGLWKYFPTKTYRDFARAEDLIYDVISEIIDHELE 304
            ..:       |...:..:.||:.:       .|.::..|:.:::...|.|:|.:..:..|....:
Mouse   219 GSLKFIHALHSMFKSTSQLLFLPK-------SLTRWTSTRVWKEHFDAWDVISEYANRCIWKVHQ 276

  Fly   305 ELKKSAACEDDEAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPG 369
            ||:..:      :.....|...::....|.:...|:..::..|..::|.|..|:..|..:..:|.
Mouse   277 ELRLGS------SQTYSGIVAELISQGSLPLDAIKANSMELTAGSVDTTAIPLVMTLFELARNPD 335

  Fly   370 AMPRILSEFCEYRDTNIL---QDALTNATYTKACIQESYRLRPTAFCLARILEEDMELSGYSLNA 431
            ....:..|... .:.:|.   |.|:::....:|.::|:.||.|....|.|||..|:.|..|.:.|
Mouse   336 VQKALRQESLA-AEASIAANPQKAMSDLPLLRAALKETLRLYPVGGFLERILSSDLVLQNYHVPA 399

  Fly   432 GTVVLCQNMIACHKDSNFQGAKQFTPERWIDPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEM 496
            ||:||..........:.|...:::.|:||:: ...:|.        .:.||.|.|.|.|:|..|:
Mouse   400 GTLVLLYLYSMGRNPAVFPRPERYMPQRWLE-RKRSFQ--------HLAFGFGVRQCLGRRLAEV 455

  Fly   497 EVVLLLAKMVLAFDVSFVK--PLETEFEFLLAPKT 529
            |::|||..::..|.|..::  .::..:.|:|.|.:
Mouse   456 EMMLLLHHILKTFQVETLRQEDVQMAYRFVLMPSS 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	108/449 (24%)
Cyp11b2	NP_034121.4	cytochrome_P450	72..496	CDD:477761	108/450 (24%)