Protein Alignment shd and Cyp11a1

DIOPT Version :9

• Sequence 1: NP_001261843.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_062753.3
• Gene: Cyp11a1 / 13070
• MGIID: 88582
• Length: 526
• Species: Mus musculus
• Alignment Length: 503
• Identity: 119/503 - (23%)
• Similarity: 214/503 - (42%)
• Gaps: 70/503 - (13%)

  Fly    57 RGIWDIPGPKRIPFLGTKWIFLLFFRRYKMT-KLHEVYADLNRQYGDIVLEVMPSNVPIVHLYNR 120
            |...:||.|.     ...|:.|..|.|...| |:|.......::||.|..|.: ..:..|::.:.
Mouse    43 RSFNEIPSPG-----DNGWLNLYHFWRESGTQKIHYHQMQSFQKYGPIYREKL-GTLESVYIVDP 101

  Fly   121 DDLEKVLKYPSKYPFR---PPTEIIVMYRQ--SRPDRYASVGIVNEQGPMWQRLRSSLTSSITSP 180
            .|...:.......|.|   ||.   |.|.|  .||     :|::.:....|::.|..|...:.:|
Mouse   102 KDASILFSCEGPNPERFLVPPW---VAYHQYYQRP-----IGVLFKSSDAWKKDRIVLNQEVMAP 158

  Fly   181 RVLQNFLPALNAVCDDFIELLRARRDPDTLVVPNFEELANLMGL----------EAVCTLMLGRR 235
            ..::||:|.|..|..|||::|..|...        :...|..|:          |::.:::.|.|
Mouse   159 GAIKNFVPLLEGVAQDFIKVLHRRIKQ--------QNSGNFSGVISDDLFRFSFESISSVIFGER 215

  Fly   236 MGFL--AIDTKQPQKISQLAAAVKQLFISQRDSYYGLGL----WKYFPTKTYRDFARAEDLIYDV 294
            ||.|  .:|.:..:.|:    ||.|:|   ..|...|.|    ::...|||::|.|.|.|:|::.
Mouse   216 MGMLEEIVDPEAQRFIN----AVYQMF---HTSVPMLNLPPDFFRLLRTKTWKDHAAAWDVIFNK 273

  Fly   295 ISEIIDHELEELKKSAACEDDEAAGLRSIFLNILELKDLDIRDKKSAIIDFIAAGIETLANTLLF 359
            ..|...:...:|::..     :.:....:..::|....|..::.::.|.:.:|.|::|.:.||.:
Mouse   274 ADEYTQNFYWDLRQKR-----DFSQYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQW 333

  Fly   360 VLSSVTGDPGAMPRILSEFCEYR--DTNILQDALTNATYTKACIQESYRLRPTAFCLARILEEDM 422
            .|..:..:......:.:|....|  ....:...:......||.|:|:.||.|.:..|.|....|:
Mouse   334 NLYEMAHNLKVQEMLRAEVLAARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYTVNDL 398

  Fly   423 ELSGYSLNAGTVVLCQNMIACHKDSNFQGAKQFTPERWIDPA--TENFTVNVDNASIVVPFGVGR 485
            .|..|.:.|.|:|...:.........|....:|.|.||::.:  |.:|.        .:.||.|.
Mouse   399 VLRNYKIPAKTLVQVASFAMGRDPGFFPNPNKFDPTRWLEKSQNTTHFR--------YLGFGWGV 455

  Fly   486 RSCPGKRFVEMEVVLLLAKMVLAF--DVSFVKPLETEFEFLLAPKTPL 531
            |.|.|:|..|:|:.:||..::..|  :|..::.:.|:|..:|.|:.|:
Mouse   456 RQCLGRRIAELEMTILLINLLENFRIEVQNLRDVGTKFSLILMPENPI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_001261843.1	p450	63..528	CDD:299894	115/492 (23%)
Cyp11a1	NP_062753.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..49		1/5 (20%)
		p450	49..507	CDD:278495	117/497 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820