Protein Alignment shd and cyp24a1

DIOPT Version :10

• Sequence 1: NP_996074.1
• Gene: shd / 39592
• FlyBaseID: FBgn0003388
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_012808417.2
• Gene: cyp24a1 / 100497429
• XenbaseID: XB-GENE-479201
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 139/540 - (25%)
• Similarity: 232/540 - (42%)
• Gaps: 69/540 - (12%)

  Fly    28 YLRPLLKN------------TLLEDFYHAELIQPEAPKRRRRGIWDIPGPKRIPFLGTKWIFLLF 80
            :|..|||:            |.:.|....||   .||......:..:|||.::|.||:   .|..
 Frog     9 FLGMLLKSRSISVQHSIPTATAVCDLKEEEL---PAPSSCPHSLAALPGPTKLPILGS---LLDI 67

  Fly    81 FRRYKMTKLHEVYADLNRQYGDIVLEVMPSNVPIVHLYNRDDLEKVLKYPSKYPFRPPTEIIVMY 145
            .|:..:.:.||..|..::|:|.| ..:...:...||:.....||.:.:..|.||.|...:....|
 Frog    68 LRKGGLKRQHEALASYHKQFGKI-FRMKLGSFDSVHIGAPCLLEALYREESNYPKRLEIKPWKAY 131

  Fly   146 RQSRPDRYASVGIVNEQGPMWQRLRSSLTSSITSPRVLQNFLPALNAVCDDFIELLRARRDPDTL 210
            |..|.:.|   |::..:|..|||:||:....:..|..:......:|.|..||::.:.:..|.|..
 Frog   132 RDYRDEAY---GLLILEGKDWQRVRSAFQQKLMKPTEVGKLDTKINEVLVDFMKRIDSVCDEDGT 193

  Fly   211 VVPNFEELANLMGLEAVCTLMLGRRMGFLAIDTKQP---QKISQLAAAVKQLFISQRDSYYGL-- 270
            :...:.|| |...||::|.::..:|.|||     ||   ::......|:|.:.     |.:||
 Frog   194 IEDLYCEL-NKWSLESICLVLYEKRFGFL-----QPNLGEEAQNFITAIKMMM-----STFGLMM 247

  Fly   271 ----GLWKYFPTKTYRDFARAEDLIYDVISEIIDHELEELKKSAACEDDEAAGLRSIFLNILELK 331
                .|.|...||.::|...|.|.|:......||..|.:|         .:.|.......|....
 Frog   248 VTPVELHKSLNTKIWKDHTHAWDSIFKTAKCHIDRRLTKL---------SSKGSEDFLCTIYNDS 303

  Fly   332 DLDIRDKKSAIIDFIAAGIETLANTLLFVLSSVTGDPGAMPRILSEFCEYRDTNILQDA------ 390
            .|..::..:.|.:.:...:||.||:||:.:.:::.:|....::|.|.    ::.:|.|.
 Frog   304 KLSKKEMYATITEMLIGAVETTANSLLWAIFNISRNPHIQKKLLEEI----ESVLLPDQVPTADD 364

  Fly   391 LTNATYTKACIQESYRLRPTAFCLARILEEDMELSGYSLNAGTVVLCQNMIACHKDSNFQGAKQF 455
            :.|..|.|||::||.|:.|:.....|.|:::..|..|.|..|||:...:.:.......|....||
 Frog   365 IRNMPYLKACLKESMRITPSIPFTTRTLDKETVLGDYVLPKGTVLTINSHVLGSNQECFDNWNQF 429

  Fly   456 TPERWIDPATENFTVNVDNASIVVPFGVGRRSCPGKRFVEMEVVLLLAKMVLAFDVSFV--KPLE 518
            .||||:...      |..|....||||:|:|.|.|:|..|:::.|.|..::..:::...  .|:|
 Frog   430 RPERWLQQK------NTINPFAHVPFGIGKRMCIGRRLAELQLQLTLCWLIRKYEIVATDNDPVE 488

  Fly   519 TEFEFLLAPKTPLSLRLSDR 538
            |.....|.|...|.:....|
 Frog   489 TLHLGTLMPSRELPVAFHRR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shd	NP_996074.1	CYP24A1-like	98..532	CDD:410677	116/450 (26%)
cyp24a1	XP_012808417.2	CYP24A1	84..502	CDD:410738	116/451 (26%)