DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gbs-70E and Ppp1r3f

DIOPT Version :10

Sequence 1:NP_648708.2 Gene:Gbs-70E / 39588 FlyBaseID:FBgn0036428 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_001277503.1 Gene:Ppp1r3f / 54646 MGIID:1859617 Length:800 Species:Mus musculus


Alignment Length:316 Identity:65/316 - (20%)
Similarity:102/316 - (32%) Gaps:116/316 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   148 SNGEVSRGPKKHVIFADDE-GLSLTEVRVMSEPSNVPPYWSMKFL-------------------- 191
            ::.|.:..|:: |:|||:. ||.|.::| ...|...|....|...                    
Mouse    26 ASAEAAVAPRR-VLFADEALGLPLAQLR-RYRPWGGPGAGKMAAATGQDGGGGGADEEDDGEDGD 88

  Fly   192 --EQITQGLVSPHPP--------DQWTVDFKQPASDYLSFRQKIERDFVSLENV----------- 235
              |:..:....|.||        ......|..|.:  |...:::.|..|.||.:           
Mouse    89 EGEEEEEAFPDPSPPCPVPAGGGFYLVPTFSLPPA--LGRLERLGRVMVELEALLPPPGAVPGGS 151

  Fly   236 ---IVKDEESIVVGTIKVKNIDFQKEIIVRVTWDDWKSQQDIFCTYARAYGPAT----------- 286
               :......:|.|.::|.|..|:|.:.||.:.|.|.:    ||.:...|.|.:           
Mouse   152 GVWVPGGRPPVVRGLVRVLNRSFEKAVHVRASHDGWAT----FCDHPARYVPRSPPGAGVGGTGA 212

  Fly   287 -------------------------CAHVVFDTFSFKITLPPSSK---RLEFCICYRTNETEYWD 323
                                     |.    |.|:|::.....:.   ||:|.:.|.|.|..:|.
Mouse   213 GDPLLDPGLGLGPGQMSASSPDDGGCT----DRFAFQLPFAEGASDGARLDFVVRYETPEGTFWA 273

  Fly   324 NNDGKNYTISKRSPFYYNALSPYDKGQNRNSSQQIRSTLTDALAKVQDQNGWHQEP 379
            ||.|:|||:..|       ::|             ..|.|||....|.|.....||
Mouse   274 NNHGRNYTVLLR-------IAP-------------APTPTDAEGLPQQQQLQQLEP 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gbs-70ENP_648708.2 PBD_PPP1R3 <136..198 CDD:455118 14/72 (19%)
CBM_21 224..332 CDD:427265 34/160 (21%)
Ppp1r3fNP_001277503.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..30 0/3 (0%)
PP1-binding motif 36..39 1/3 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 53..108 7/54 (13%)
CBM_21 163..282 CDD:427265 30/126 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 201..235 0/33 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 332..353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 418..440
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 567..601
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 664..689
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 723..744
Blue background indicates that the domain is not in the aligned region.

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